Leila Kamali-Dolatabadi
Department of Neuroscience, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran
[ 1 ] - P 16: The Effect of Reducing CCL11 on Multiple Sclerosis Treatment by Using Heterochronic Parabiosis Techniques
Introduction: Multiple sclerosis is a chronic neuroinflammatory disease that leads to distribute neurodegeneration in the grey and white matter of the brain. In MS, age-related iron accumulation, chronic oxidative injury and activation of microglia are key factors to create neurodegeneration. Also concentration of CCL11 is increased in multiple sclerosis. CCL11 can amplify glu...
[ 2 ] - Effects of amitriptyline and fluoxetine on synaptic plasticity and TNF-α level at hippocampus of streptozotocin-induced diabetic rats
Introduction: Studies have indicated that diabetes mellitus impairs hippocampus. Diabetes increases the risk of depression and treatment with antidepressants may affect learning and memory. The aim of this study was to evaluate the effects of amitriptyline and fluoxetine on synaptic plasticity and TNF-α level in the hippocampus of streptozotocin-induced diabetic rats. Methods: Experimenta...
[ 3 ] - Curcumin Improves Memory Impairment and Restores Irregular Neuronal Distribution In the Hippocampal CA1 Region After Global Cerebral Ischemia in Male Rats
Purpose: Global Cerebral Ischemia (GCI) causes neuronal damage that leads to neurological and cognitive impairments. Curcumin has anti-inflammatory, antioxidant and neuroprotective properties which makes it a potential candidate for improving GCI-induced impairments. The aim of this study was to investigate the effects of curcumin on the neurological and memory deficits as well as spatial neuro...