آرپنائی, ایوب
علوم پزشکی مازندران
[ 1 ] - ساخت و تعیین ویژگی ذرات نانوکامپوزیتی متخلخل سیلیکای مغناطیسی برای کاربردهای پزشکی و بررسی سمیت سلولی آنها
Background and purpose: One of the most important challenges in nanomedicine is timely diagnosis and effective treatment of chronic disease. The aim of this research was to synthesize and characterize 3-layered magnetic silica nanocomposite with simultaneous application as a contrast agent in magnetic resonance imaging (MRI) and for drug delivery. Materials and methods: In this research, magne...
[ 2 ] - The Effects of Organic Solvents on the Physicochemical Properties of Human Serum Albumin Nanoparticles
Background: Recently, applications of albumin nanoparticles as drug delivery carriers have increased. Most toxicology studies have shown that surface chemistry and size of nanoparticles play an important role in biocompatibility and toxicity. Objective: The effect of desolvating agents with different chemical properties on the size of synthesized HSA NPs was investigated. Materials and Method...
[ 3 ] - Preparation and Characterization of Double Shell Fe3O4 Cluster@Nonporous SiO2@Mesoporous SiO2 Nanocomposite Spheres and Investigation of their In Vitro Biocompatibility
Background: Multifunctional core-shell magnetic nanocomposite particles with tunable characteristics have been paid much attention for biomedical applications in recent years. A rational design and suitable preparation method must be employed to be able to exploit attractive properties of magnetic nanocomposite particles. Objectives: Herein, we report on a simple approach for the synthesis of m...
[ 4 ] - Optimizing Primary Recovery and Refolding of Human Interferon-b from Escherichia coli Inclusion Bodies
Background: The refolding of proteins from inclusion bodies is affected by several factors, including solubilization of inclusion bodies by denaturants, removal of the denaturant, and assistance of refolding by small molecule additives. Objectives: The purpose of this study was optimization of recombinant human interferon-b purification in order to achieve higher efficiency, yield, and a produ...
[ 5 ] - Investigation of Desulfurization Activity, Reusability, and Viability of Magnetite Coated Bacterial Cells
Background: Magnetic separation using magnetic nanoparticles can be used as a simple method to isolate desulfurizing bacteria from a biphasic oil/water system. Objectives: Magnetite nanoparticles were applied to coat the surface of Rhodococcus erythropolis IGTS8 and Rhodococcus erythropolis FMF desulfurizing bacterial cells, and the viability and...
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