ابراهیمی, احمد
استادیار، مرکز تحقیقات سلولی و مولکولی، پژوهشکده علوم غدد درون‌ریز و متابولیسم، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران
[ 1 ] - پلی مورفیسم -T786C در ژن نیتریک اکساید سنتاز اندوتلیالی (eNOS) به عنوان یک فاکتور خطرگویا در بیماران ایرانی مبتلا به اختلالات عروق کرونری
Background and purpose: Endothelial-derived nitric oxide (NO) is a major contributor in regulating myocardial function and has been implicated in development of coronary artery disease (CAD) as the most common type of cardiovascular disease. It is synthesized in the human body from L-arginine by constitutive endothelial NOS (eNOS) as one out of three known isoforms of NO synthase (NOS) involved...
[ 2 ] - استحکام باند بین سه نوع فایبر پست و سه ناحیه از عاج ریشه
Background and Aim: Debonding is the most common failure type of fiber posts. This in vitro study aimed to evaluate the bond strength of 3 different fiber posts cemented with a resin luting agent in three regions of prepared post spaces after being subjected to termocycling. Materials and Methods Thirty six mandibular first premolars were sectioned at the cemento-enamel junction and were treat...
[ 3 ] - شیوع ﭘﻠﻲﻣﻮرﻓﻴﺴﻢ پروترومبین G20210A در جنوب ایران
Background: There are many genetic and non-hereditary risk factors that are known to causes venous thromboembolic (VTE) disorders, Cardiovascular diseases and types of cancer. One of these is the Prothrombin G20210A mutation. Prothrombin mutation (guanine to adenine G→A) at nucleotide position 20210, which is present in the 3′ untranslated region of the prothrombin gene. Prothrombin G20210A mut...
[ 4 ] - عدم ارتباط میان پلی‌مورفیسم rs9340799 ژن Estrogen receptor alpha (ESR1) و استعداد ابتلا به اندومتریوز در زنان ایرانی
Background: The major issue to address in endometriosis etiology is to identify the genetic changes in the disease and their occurrence in different populations. Uncovering these genetic changes may be important in developing potential biomarkers for early diagnosis and prognosis of endometriosis. Among all endometriosis susceptibility genes studied before, convincing association has been found...
[ 5 ] - نقش پلی‌مورفیسم‌های شایع ژن گلوتاتیون -S ترانسفراز در استعداد ابتلا به میوم رحمی
Background: Uterine myomas are benign tumors of the uterus and the most common solid pelvic tumors causing symptoms in approximately 25% of women in their reproductive years. However, its etiology and pathogenesis remain obscure there is increasing evidence that endometriosis is inherited as a complex genetic trait. Recent studies indicated the involvement of glutathione S-transferase M1 (GSTM1...
[ 6 ] - ارتباط بین پلی‌مورفیسم ((Ile105Val ژن گلوتاتیون S- ترانسفراز P1 (GSTP1) و خطر ابتلا به لیومیوم رحمی در جمعیت ایرانی
Background: Uterine leiomyoma is one of the most common benign smooth muscle tumors occurring in 20-40% of women worldwide in their reproductive years. Recent studies revealed that estrogen plays an important role in the pathogenesis of this disease. Since glutathione S-transferase (GST) gene family are involved in the biosynthesis of estrogen, the prior probability that variants at this locus ...
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