رنجی, نجمه
استادیار، گروه ژنتیک، دانشکده علوم، واحد رشت،دانشگاه آزاد اسلامی، رشت، ایران
[ 1 ] - جهش های ژن gyrA در جدایه های سودوموناس آئروزینوزا مقاوم به فلوروکوئینولون ها در استان گیلان
Background and purpose: Pseudomonas aeruginosa is an opportunistic pathogen in patients with chronic respiratory disease or in immunocompromised hosts. This bacterium shows intrinsic and acquired resistance to diverse antimicrobial agents. An important mechanism of resistance to fluoroquinolones in P. aeruginosa is the mutation in gyrA, a subunit of topoisomerases II. The aim of this study was ...
[ 2 ] - بررسی مقاومت آنتیبیوتیکی و فراوانی ژن های بتالاکتاماز وسیعالطیف TEM و SHV در سویههای کلبسیلا پنومونیه جداشده از نمونههای خون نوزادان بستری در برخی بیمارستانهای شهر رشت
زمینه و اهداف: کلبسیلا پنومونیه یکی از عوامل شایع در عفونتهای مهم بیمارستانی می باشد. هدف از این مطالعه تعیین میزان فراوانی ژن blaTEM و blaSHV در سویه های کلبسیلا پنومونیه جدا شده از عفونت خون از نمونه های کلینیکی شهر رشت می باشد. مواد و روش ها: در این مطالعه، ۱۶۳ ایزوله جدا شده از نمونه های خون بیمارستان های شهر رشت از نظر حساسیت آنتی بیوتیکی به روش انتشار دیسک و تست غربالگری به روش دیسک ...
[ 3 ] - Mutation Identification in Exon 10 of SLC26A4 Gene in Individuals with Hearing Loss in Guilan Province
Introduction: Mutation in SLC26A4 gene is one of reason of syndromic and non-syndomic hearing loss. Mutation in this gene is reported to be the second most common cause of deafness in the worldwide, after GJB2 gene. The aim of this study was to evaluate mutations in exon 10 of SLC26A4 gene in individuals with hearing loss in Guilan province. Materials and Methods: In this descriptive cross-sect...
[ 4 ] - The Relationship between Gastric Carcinogenesis Susceptibility and Some SNPs in MicroRNA Genes in General Population of Ardabil Province
Background & Objectives: Gastric cancer is the fourth most common cancer in the world and Ardabil province is in the top ranks in the world. MicroRNAs are non-coding RNA molecules with a length of 18 to 21 nucleotides and due to their regulatory role in post- transcriptional gene expression; single nucleotide polymorphisms (SNPs) could affect their function on target genes regulation. Methods: ...
[ 5 ] - Synthesis of Titanium Oxide Nanoparticles Functionalized by Glutamine and Conjugated to Thiosemicarbazide and their Effect on the Expression of the CASP3, Bcl2, and BAX genes
Introduction: The increasing trend of cancer morbidity and mortality is a major human health concern, indicating the necessity for the design and introduction of novel anticancer compounds. The use of nanotechnology products is a new approach to cancer treatment. Therefore, the current study was performed to synthesize Titanium Dioxide nanoparticles (NPs) functionalized with glutamine and conju...
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