بخردنیا, احمدرضا
. استاد، گروه شیمی دارویی، مرکزتحقیقات علوم دارویی، دانشگاه علوم پزشکی مازندران، ساری، ایران
[ 1 ] - سنتز (1-H) پیرازولو [4،5 -b] کینوکسالین با پتانسیل اثر ضد میکروبی
Background and purpose: Increasing resistance of microbes to antimicrobial drugs necessitates the production of new compounds of more extensive activity together with low toxicity. Compounds containing quinoxaline and pyrazole cycles comprise important group of nitrogen-bearing heterocyclic compounds. These scaffolds possess a wide spectrum of biological effects including antimicrobial and anti...
[ 2 ] - سنتز مشتقات جدید 2 و 3-دی آریل کینوکسالین و کینوکسالین اکسید با پتانسیل اثرات ضد سرطانی و ضد میکروبی
Background and purpose: Quinoxaline derivatives are standing interest of people who work on anti-cancer drugs. There are many reports about using these agents as DNA cleaving, transglutaminase 2 inhibitor, topoisomerase II inhibitor and tumor antibiotic. Other drugs used in treatment of tuberculosis such as isoniazid, pyrazinamide and rifampin have similar structures to quinoxaline and quinoxal...
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