اربابی, آویشن

دانشجوی داروسازی، دانشکده داروسازی، دانشگاه علوم پزشکی مازندران، واحد بین الملل رامسر، رامسر، ایران

[ 1 ] - سنتز (1-H) پیرازولو [4،5 -b] کینوکسالین با پتانسیل اثر ضد میکروبی

Background and purpose: Increasing resistance of microbes to antimicrobial drugs necessitates the production of new compounds of more extensive activity together with low toxicity. Compounds containing quinoxaline and pyrazole cycles comprise important group of nitrogen-bearing heterocyclic compounds. These scaffolds possess a wide spectrum of biological effects including antimicrobial and anti...

[ 2 ] - سنتز مشتقات هیدرازیدی از ساخارین و بررسی فعالیت شلاته‌ کنندگی آن‌ها

Background and purpose: Zinc (Zn), copper (Cu) and iron (Fe) are essential minerals required for a variety of biomolecules to maintain the normal structure, function, and proliferation of cells. Abnormal metabolism of heavy metals can lead to several chronic pathogenesis. In this study, two new saccharin hydrazide derivatives were synthesized and their chelatory activities were evaluated. Mate...

[ 3 ] - Green Chemical Synthesis and Biological Evaluation of Novel N-substituted Rhodanine Derivatives as Potential Antifungal Agents

Background and purpose: In medicinal chemistry, molecules containing rhodanine(2-thiazolidine-4-one) ring as a magic multifunctional privileged structural and functional scaffold show a broad range of potent pharmacological properties containing anti-microbial, antiviral, anti-diabetic, and anti-convulsant effects. Evidence suggests that the activity of the rhodanine derivative correlates with ...