محمودزاده, امیر

[ 1 ] - بررسی اثر ملیتین بر میزان بیان پروتئین Rac1 به عنوان مارکر متاستاز در سلول‌های سرطان معده رده AGS

Introduction: Understanding the molecular mechanisms of metastasis is important for the design and effective use of novel therapeutic strategies in order to combat metastases. One class of molecules that has been implicated in metastasis is Rac1. Regarding complications of conventional therapies such as chemotherapy, current studies are evaluating natural compounds with anticancer Properties. M...

[ 2 ] - بررسی فعالیت ضد باکتریِ اجزاء زهر عقرب ایرانی Hemiscorpius lepturus

زمینه و اهداف: جستجو جهت یافتن پادزیست‌هایی که باعث القاء مقاومت ژنتیکی در باکتری‌ها نمی‌گردند از اهمیت زیادی برخوردار است. مطالعات زیادی، جداسازی پادزیست های طبیعی از جمله پپتیدهای ضد میکروبی را از منابع مختلف گزارش کرده‌اند. این پپتید ها از منابعی چون انسان، مهره‌داران، بی‌مهرگان، حشرات، حیوانات سمی و گیاهان استخراج‌شده و نقش دفاعی ذاتی دارند. هدف از این مطالعه تخلیص پلی پپتیدهای ضد باکتری عق...

[ 3 ] - Identifying Requirements of a Self-care System on Smartphones for Preventing Coronavirus Disease 2019 (COVID-19)

Background: Smartphone applications play a pivotal role in management, providing care and preventing infectious diseases. It also has the potential impact on supportive and self-care. This study aimed to identify the requirements for a smartphones self-care system to prevent corona-virus (COVID-19). Materials & Methods: This was a descriptive study performed in two main stages in 2020. At the ...

[ 4 ] - Thrombotic Thrombocytopenic Purpura: Diagnosis and Treatment

Thrombotic Thrombocytopenic purpura (TTP) is a rare thrombotic microangiopathic disease, associated with thrombocytopenia and hemolytic anemia. It is caused by an enzymatic dysfunction responsible in cleavage of blood clotting factors. In this study we have tried to review the available approaches in diagnoses of the disease as well as treatment strategies. Based on the what the current review ...