رهنما, ریحانه

دانشگاه علوم پزشکی اصفهان

[ 1 ] - بررسی شیوع فراوانی پلی‌مورفیسم rs3761549 ژن foxp 3 در بیماری مولتیپل اسکلروزیس

Introduction: Multiple sclerosis (MS) is a demyelinating disease of central nervous system. Lack of regulation in inflammatory responses is considered to be a key element in the auto reactive immune response in MS. The FOXP3 transcription factor is predominantly expressed by the Treg cell lineage and appears to act as a master regulator of effector T cell activation. Therefore, this study aimed...

[ 2 ] - RAGE p.82G>S Polymorphism Is Not Associated with the Risk of Multiple Sclerosis in Iranian Population

Background and Aims: Multiple sclerosis (MS) is known as a partially inheritable inflammatory autoimmune disease which involves the nervous system. Different studies suggest that immune dysregulation has an important role in the pathogenesis of MS, but its exact pathomechanism has not yet been explicated. The receptor for advanced glycation end products (RAGE) is a member of the immunoglobulin ...