وهابی برزی, نسترن
دانشگاه آزاد اسلامی
[ 1 ] - بررسی شیوع پلیمورفیسم در ژن کدکننده آنزیم آروماتاز با خطر ابتلا به سرطان پروستات در شمال هندوستان
Background: A series of biochemical reactions are involved in the endogenous production of estrogens. Their final and rate-limiting step is catalyzed by aromatase belonging to the class XIX of cytochrome P450. CYP19 is a key enzyme for estrogen synthesis in males. It catalyzes the irreversible conversion of androstenedione and testosterone to estrone and estradiol-17&beta, respectively. Aromata...
[ 2 ] - بررسی نقش ژن CYP1B1 در سرطان پروستات در دو جمعیت ایرانی و هندی
Prostate cancer (PCa) is the most common non-skin cancer and the second leading cause of cancer death among men in the world. Growth, maintenance and the expression of genes involved in the production of steroids, may alter the susceptibility of prostate cancer. One such gene, CYP1B1 (cytochrome P450, family 1, subfamily B, polypeptide 1) is involved in the activation of many carcinogens and i...
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