دده‌خانی, سونیا

دانشکده علوم، دانشگاه ارومیه

[ 1 ] - بررسی اثرات ضد تکثیری داروی هیدرالازین بر روی سلو‌ل‌های سرطانی رده K562 (لوسمی میلوئید مزمن)اثر هیدرالازین بر سلول‌های K562

Introduction: Cancer is the second leading cause of death in the world and among the types of cancer, leukemia is one of the deadliest. Chronic myeloid leukemia (CML) is the best known types of leukemia. Hydralazine is in the cardiovascular medical group, which is considering as inhibitory factor on the proliferation of cancer cells by knowing its inhibitory effects on DNA methyltransferase. Th...

[ 2 ] - The Anti-cancer effects of Celastrol on K562 cell line

  Background and Objective: The level of NF-κB factor expression (a transcriptional factor which increases the expression of inflammatory genes) is often increased in various human cancers. Therefore, NF-κB inhibitors such as Celastrol may prevent cancer development. The purpose of this study was to evaluate the anticancer effects of Celastrol on K562 cells proliferation. Materials and Methods:...

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