شکاری, محمد

[ 1 ] - بررسی بیان ژن اکسپورتین5 (XPO5) در بیماران مبتلا به سرطان پستان

Background and objectives: Deregulation in the expression of microRNAs is involved in the pathogenesis of various malignancies. Impaired microRNAs processing pathway is one possible mechanism for global deregulation of the miRNAs. Exportin 5 (XPO5) is a key member of this pathway that links nuclear and cytoplasmic steps of miRNAs biogenesis together. XPO5 deregulation has been reported in ...