ابوالحسنی , محسن
انستیتو پاستور ایران، آزمایشگاه هیبریدوما ، بخش ایمونولوژی
[ 1 ] - بررسی اثر محافظت بخش تجویز لاکتوباسیلوس اسیدوفیلوس و لاکتوباسیلوس کازئی درکاهش شدت عفونت ناشی از کاندیدا آلبیکنس در مدل موش BALB/c
Received: 12 Sep, 2012 Accepted: 15 Des, 2012 Abstract Background & Aims : Candida albicans is one the widespread opportunistic fungal causing disease in human. Probiotics are useful bacteria with immunomodulatory effects on different spectrum of diseases. In this study the protective effect of Lactobacillus acidophilus and Lactobacillus Casei in reducing the Candida albicans infection in...
[ 2 ] - Obituary: Professor Fereydoun Malekzadeh (1933-2012)
We were greatly saddened to hear the news of Professor Fereydoun Malekzadeh's death at age of 79 in September 9, 2012. Professor Malekzadeh was a distinguished and highly respected Iranian Microbiologist and a member of the editorial board of the Iranian Biomedical Journal since October 1997. He was born in 1933 in city of Tabriz in Province of Azarbaijan, Iran. After graduated from high school...
[ 3 ] - Heat Shock Proteins Enriched-Promastigotes of Leishmania major Inducing Th2 Immune Response in BALB/c Mice
Background: Heat shock proteins (HSP) are highly conserved molecules with many immunological functions. They are highly immunogenic with important role in cancer immunotherapy and in vaccine development against infectious diseases. As adjuvant, HSP can augment the immunogenicity of weak antigens and can stimulate antigen presenting cells. Although vaccines have been successful for many infec...
[ 4 ] - Production and Characterization of Monoclonal Antibodies Recognizing a Common 57-kDa Antigen of Leishmania Species
Background: The therapy of leishmania infection is difficult and each year 1.5 million new cases of cutaneous leishmaniasis and 500,000 new cases of visceral leishmaniasis are estimated, therefore, there is a need for an effective vaccine. Monoclonal antibody (mAb) is one of the suitable methods for isolation and purification of leishmania antigens. In this report, we produced several mAb aga...
[ 5 ] - Partial Purification of a Potent Immunosuppressive Factor Excreted from Leishmania major Promastigote and Amastigote
Recent scientific evidence indicates that distinct patterns of susceptibility in BALB/c mice to Leishmania major infection are attributable to the differential expansion of distinct CD4+ T-cell subsets and their cytokines production. Production of the Th1 cytokine IFN-g is associated with resistance, whereas production of the Th2 cytokines IL-4 and IL-10 are associated with extreme susceptibili...
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