شیخپور, رباب
گروه پرستاری، دانشکده پزشکی، واحد یزد، دانشگاه آزاد اسلامی، یزد،
[ 1 ] - تأثیر هورمون پروژسترون بر میزان پروتئین p53 در رده سلولی T47D سرطان پستان
Background & Aims: Breast cancer is the most common cancer in women. Nearly 50% of breast cancers are dependent to sex hormones, and the effects of these hormones are mediated by their binding to specific receptors. Also p53 protein is mutated in about half of cancers including breast cancer and high level of p53 protein is a common feature of many human malignant cancers. Given that T47D cell...
[ 2 ] - تشخیص سرطان پستان با استفاده از برآورد ناپارمتری چگالی احتمال مبتنی بر روشهای هستهای
Introduction: Breast cancer is the most common cancer in women. An accurate and reliable system for early diagnosis of benign or malignant tumors seems necessary. We can design new methods using the results of FNA and data mining and machine learning techniques for early diagnosis of breast cancer which able to detection of breast cancer with high accuracy. Materials and Methods: In this study,...
[ 3 ] - Immunophenotype evaluation of Non-Hodgkin’s lymphomas
Background: Non-Hodgkin’s lymphoma (NHLs) is known as a heterogeneous group of malignant lymphoproliferative disorders. NHLs are classified into B cell and T cell types. Immunophenotypical assessment of the biopsy specimens can help diagnose NHLs. Methods: In this study, 77 patients with B cell and T cell lymphoma were selected from Shahid Sadoghi hospital during 2010 to 2...
[ 4 ] - The Role of Adiponectin in Prostate Cancer: A Narrative Review
Prostate cancer (PCa) is the most common type of cancer among men over 60 years old. The aggressiveness and mortality of PCa can be correlated with obesity. Adipose tissue-derived cytokines such as adiponectin may explain the correlation between PCa and obesity. Since the correlation between adiponectin and aggressive PCa is still not fully evaluated, we aimed to investigate the probable role o...
[ 5 ] - Leptin in Breast Cancer: Its Relationship with Insulin, Estrogens and Oxidative Stress
Breast cancer is the most common cancer in women. Several risk factors such as age, family history of breast cancer, marital status, early menarche and late menopause are related to breast cancer. Obesity is also a main health problem associated with breast cancer incidence and subsequent mortality. Association between obesity and expansion of breast cancer may be due to excessive sex steroid h...
[ 6 ] - Relation between Estrogen and Progesterone Receptor Status with p53, Ki67 and Her-2 Markers in Patients with Breast Cancer
Background: Breast cancer is the most common cancer in women, containing approximately one third of all illnesses in women. Assessment of molecular markers is valuable in predicting the outcome of disease and decision making for optimal treatment. The purpose of this study was to determine the relationship between estrogen and progesterone receptors with Her-2, Ki67, P53, and clinicopathologica...
[ 7 ] - The Evaluation of Immunophenotypes in Diffuse Large B Cell Lymphoma: A Single Center Study
Background: Diffuse large B-cell lymphoma (DLBCL) is an aggressive malignancy of mature B lymphocytes. It is known as a heterogeneous disease with variable therapeutic responses and alternative therapies. Morphological and immunophenotypical evaluation of the biopsy specimens can help diagnose DLBCL. Methods: In the current study, 44 patients were chosen from Shaheed Sadoghi Hospital (2010&nda...
[ 8 ] - The effect of Aloe vera syrup on prevention of fever and neutropenia in children with acute lymphoid leukemia
Background: Given that few studies regarding the effect of Aloe vera (A. vera) on prevention of fever and neutropenia on acute lymphoid leukemia (ALL) disease, the aim was to evaluate the effect of A.vera on prevention of fever and neutropenia in children with ALL. Materials and Methods: This randomized clinical trial study was conducted on 60 children with mean age 5.6± 2.9 years in Oncology ...
[ 9 ] - Different Biomarkers of Acute kidney Injury in Cancer Patients
Acute Kidney Injury (AKI) occurs if the kidneys suddenly lose their ability to remove waste products. When the kidneys lose their ability to filter, dangerous levels of waste products can accumulate, which can upset the chemical composition of the blood and urine. Chemotherapy is one of the methods used to treat or temporarily reduce cancer by using certain medications. The main task of this tr...
[ 10 ] - The role of cytokine and its relation to depression and infection complications in pediatric cancer
Inflammation plays a critical role in the progression of cancer in children. On the other hand, children with cancer experience abnormal activation of the inflammatory system. Moreover, it is known that these patients have a predisposition to depression. According to studies, moderate to severe depression was observed in about 63% of children with cancer and acute illness. Therefore, identifyin...
[ 11 ] - The effect of ifosfamide and mesna in the treatment of children with various types of cancer
Background: Given that various types of cancer are major causes of death among children and there is no comprehensive study investigating the simultaneous effect of ifosfamide and mesna in the treatment of patients with various types of cancer in our country, this study aimed to assess the effect of ifosfamide and mesna in the treatment of children with various types of cancer. Materials and M...
[ 12 ] - The effect of erythropoietin on blood parameters in thalassemia intermedia patients
Background: β-thalassemia is the most common hereditary disease in Iran, and more than 2 million carriers of β-thalassemia live in Iran. On the other hand, our country is located in the thalassemia belt, and no comprehensive study has been conducted regarding the effect of erythropoietin on blood parameters in thalassemia intermedia patients in our region. Therefore this study aimed to investig...
[ 13 ] - Evaluation of the prognostic value of CD117 and CK20 biomarkers in urinary bladder carcinoma
Background: Over-expression of CD117 and cytokeratin 20 (CK20) is seen in many malignancies. Given that few studies have been conducted regarding the role of these biomarkers in the etiology of bladder tumours, this study aimed to evaluate the prognostic value of CD117 and CK 20 biomarkers in the benign and malignant tumours of urinary bladder carcinoma. Methods: This case-control study was co...
[ 14 ] - The effect of echinacea in the prevention of upper respiratory infections in children with acute lymphoblastic leukemia
Background: The efficacy of echinacea products to treat upper respiratory tract infections (URTI) has been shown in some studies, however, there are few studies considering the efficacy of echinacea to prevent URTI. Therefore this study aimed to assess the effect of echinacea in the prevention of URTI in these children. Materiala and Methods: This retrospective cross-sectional study was conduc...
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