قربانی, مهدی

[ 1 ] - بیان مینی ژنهای فاکتور 9 انعقادی انسانی در سلولهای کلیه انسان

Background & aims: Hemophilia B is caused by either functional deficiency or lack of the human coagulation factor IX (hFIX). The current protein-based therapy with plasma-derived proteins increases, the risk of blood-borne pathogens transmission. Therefore, replacement therapy with recombinant hFIX (rhFIX) is an attractive alternative to plasma derived hFIX concentrates. In order to express and...