Rastegar, H
Ministry of Health and Medical Education, Food & Drug Laboratory Research Center
[ 1 ] - Study the Effects of Oral Administration of Silymarin in Preventing Consequences of Ethanol on Liver during Pregnancy
Background: Alcoholic mothers who consume ethanol give birth to infants with high percentage of hepatic diseases. Alcohol can cause cellular damage in different tissues, including liver. Finding a drug which is effective and efficient in reducing ethanol misuse consequences during pregnancy can assist the decrease of harmful effects of this habit. Objective: This research aims to study the eff...
[ 2 ] - مطالعه اثر شربت عصاره برگ گیاه سنا Cassia angustifolia Vahl. بر فعالیت کبد و کلیه در موش صحرایی با استفاده از یافتههای بیوشیمیایی
مقدمه: عصاره برگ گیاه سنا به منظور تخلیه کامل کولون استفاده میشود. برای ایجاد اثر سریع و کامل این عصاره یا داروهای مشتق از آن از دوزهای بالای آنها استفاده میشود. بررسی اثر آنها به ویژه در دوزهای بالا روی کبد و کلیه که در فرایند سمزدایی نقش موثری دارند ضروری است. هدف: هدف از این مطالعه بررسی اثر شربت حاوی عصاره برگ گیاه سنا بر روی فعالیت کبد و کلیه حیوان آزمایشگاهی (موش صحرایی) است. روش ...
[ 3 ] - استخراج و تخلیص لیپوپلی ساکارید سالمونلا اینتریتیدیس و ارزیابی فعالیت تب زایی در خرگوش
زﻣﯿﻨﻪ و اﻫﺪاف: ﺑﺎﮐﺘﺮی ﺳﺎﻟﻤﻮﻧﻼ ﺟﺰو ﺧﺎﻧﻮاده آﻧﺘﺮوﺑﺎﮐﺘﺮﯾﺎﺳﻪ و ﺑﺎﺳﯿﻞ ﻫﺎی ﮔﺮم ﻣﻨﻔﯽ ﺗﺎژه دار اﺳﺖ ﮐﻪ اﮐﺜﺮ ﺳﺮوﺗﯿﭗ ﻫﺎی آن ﺗﻮاﻧﺎﯾﯽ ﺣﺮﮐﺖ دارﻧﺪ. ﻟﯿﭙﻮﭘﻠﯽ ﺳﺎﮐﺎرﯾﺪ ( ،(LPSﻋﺎﻣﻞ اﺻﻠﯽ ﺗﻌﯿﯿﻦ ﮐﻨﻨﺪه وﯾﺮوﻻﻧﺲ ﺑﺎﮐﺘﺮی اﺳﺖ ﮐﻪ ﺑﺎ اﺗﺼﺎل ﺑﻪ ﺳﻄﺢ ﺳﻠﻮل ﭘﯿﻮﻧﺪ ﺷﺪه و ﻓﻘﻂ در ﻫﻨﮕﺎم ﻟﯿﺰ ﺷﺪن ﺑﺎﮐﺘﺮی آزاد ﻣﯽ ﺷﻮد، ﺑﻪ آن اﻧﺪوﺗﻮﮐﺴﯿﻦ ﻧﯿﺰ ﻣﯽ ﮔﻮﯾﻨﺪ. ﻫﺪف از اﯾﻦ ﻣﻄﺎﻟﻌﻪ اﺳﺘﺨﺮاج LPSﺑﺎ روش ﻣﺘﺎﻧﻮل ﮐﻠﺮوﻓﺮم و آزﻣﺎﯾﺶ ﺗﺐ زاﯾﯽ اﯾﻦ ﺗﺮﮐﯿﺐ...
[ 4 ] - Determination of Biological Activity of Recombinant Reteplase Using Clot Lysis Time and Activated Partial Thromboplastin Time (APTT) Lysis Methods: A Comparative Study
Recombinant plasminogen activator (reteplase) is a third generation thrombolytic agent which has been used on coronary artery thrombosis and acute myocardial infarction. Clot lysis assay is usually considered as a unique method to evaluate biological activity of reteplase. In this study biological activity of reteplase was determined by APTT (activated partial thromboplastin time) lysis method....
[ 5 ] - Determination of Biological Activity of Recombinant Reteplase Using Clot Lysis Time and Activated Partial Thromboplastin Time (APTT) Lysis Methods: A Comparative Study
Recombinant plasminogen activator (reteplase) is a third generation thrombolytic agent which has been used on coronary artery thrombosis and acute myocardial infarction. Clot lysis assay is usually considered as a unique method to evaluate biological activity of reteplase. In this study biological activity of reteplase was determined by APTT (activated partial thromboplastin time) lysis method....
[ 6 ] - ارزیابی اثر کِرِم سیلیمارین در ضایعات ناشی از اشعه ماورا بنفش بر پوست خوکچه هندی با بهرهگیری از یافتههای بالینی و هیستوپاتولوژیک
Background: Nowadays skin damages caused by ultraviolet (U.V.) radiation from the sun were increased accordingly necessity for safe and inexpensive protective products for reducing the harmful effects of this ray is unassailable. The antiradical, anti irritation and anti-cancer properties of silymarin make it a suitable option for use in cream formulation to investigate its effect on skin disor...