آقایی, افسانه
استادیار مرکز تحقیقات انتقال خون ـ مؤسسه عالی آموزشی و پژوهشی طب انتقال خون
[ 1 ] - محاسبه تعداد و مکان بهینه مراکز مختلف جمع‌آوری خون در استان آذربایجان شرقی بر اساس مدلسازی ریاضی
چکیده سابقه و هدف در طراحی زنجیره تامین خون یکی از موضوعات کلیدی، تعیین محل مناسب مراکز جمع‌آوری خون است تا علاوه بر دسترسی آسان اهداکنندگان و نیز توزیع مناسب خون و فرآورده‌های خونی به مراکز بیمارستانی، هزینه‌های جمع‌آوری خون به حداقل رسانده شود. هدف از تحقیق حاضر، محاسبه تعداد و مکان بهینه مراکز تهیه و فرآوری، ثابت و سیار خونگیری بر مبنای تقاضای مراکز درمانی و هزینه‌های احداث و عملیاتی این م...
[ 2 ] - Different Immune Responses in Dangerous O Blood Donors
Background & Objective: Dangerous O is very important to transfusion medicine and there has been reports by Food and Drug Administration (FDA) regarding some death relating incidences. As high iso-antibody production is closely associated with different immune reactions, a survey on the different immune response of dangerous O donors can lead to understanding their immune respo...
[ 3 ] - Comparison of the effect of platelet lysate derived from umbilical cord blood and peripheral blood on the expansion and differentiation of MSCs
Abstract Background and Objectives Proliferation and differentiation of mesenchymal stem cells (MSCs) in culture media requires the presence of nutrient supplements such as bovine fetal serum (FBS), which increases the risk of prion/xenotic infections. Platelet lysates as a rich source of growth factors and cytokines can replace FBS in cell culture medium. This study aimed to compare the effe...
[ 4 ] - Plasma industry history at a glance
Abstract Background and Objectives The plasma industry started during World War II with the need for Plasma Derived Medicinal Products (PDMP). About 30 major plasma products are now commercially available, the most important of which are albumin, coagulation factors and immunoglobulin. Demand for these products is still growing, and these products have become particularly important not only in ...
[ 5 ] - Improvement of anticomplementary activity assay for the quality control of immunoglobulin product: an Iranian pilot scale study
Abstract Background and Objectives One of the side effects of immunoglobulin administration is the activation of the complement system related to the high concentration of aggregates/large polymers in the production process. Measuring anticomplementary activity (ACA) is important in pharmaceutical quality control and is a criterion of spontaneous activation of complement system in immunoglobuli...
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