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[ 1 ] - خصوصیات دموگرافیک و بالینی بیماران مبتلا به صرع میوکلونیک جوانان در اصفهان
زمینه: صرع میوکلونیک جوانان از شایعترین انواع صرعهای ژنرالیزه ایدیوپاتیک است و حدود 11- 5 درصد کلّ صرعها را تشکیل میدهد. با توجه به خصوصیات بالینی صرع میوکلونیک جوانان، این بیماری درکلینیکها به خوبی تشخیص داده نمیشود و درمان صحیح انجام نمیگیرد و این در صورتی است که پاسخ به درمان در این بیماران عالی و بیماران نیاز به درمان را در تمام طول زندگی دارند. مواد و روشها: در یک مطالعه توصیفی آ...
[ 2 ] - Cancer risk among patients with multiple sclerosis: A cohort study in Isfahan, Iran
Background: Multiple sclerosis (MS), a central nervous system (CNS) autoimmune disorder, affects 2.3 million people around the world. Cancer kills around 7.5 million people annually. Both diseases have similar risks and intertwining molecular causes. Most studies focusing on MS and cancer have found an insignificant difference or reduction in the amount of cancer found in the MS community. M...
[ 3 ] - Side Effects of bb-Interferon: A Comparative Study Among Avonex, Betaseron and Rebif
The administration of b-interferon is a recognized treatment for multiple sclerosis. The frequency of side effects is an important factor in drug or product selection. In this study, the side effects of three available b<span style="font-family: TimesNew...
[ 4 ] - The Association Between Salt and Potassium Intake With Multiple Sclerosis
Background: The number of patients with Multiple Sclerosis (MS) is increasing in Iran. Studies have shown that high sodium chloride (salt) and low potassium intake are associated with the development of MS. High physiological salt concentrations can lead to the induction of Interleukin-17 (IL-17) accompanied by the excessive generation of helper T-17 cells (Th-17). This cytokine plays a critica...
[ 5 ] - Negative Regulation of Semaphorin-3A Expression in Peripheral Blood Mononuclear Cells Using MicroRNA-497-5p
Background: Semaphorin-3A (Sema3A), as a secreted semaphorin, is an immune modulator molecule participating in the pathogenesis of autoimmune diseases. MicroRNAs (miRNAs) modulate the target-gene expression at the post-transcriptional level. It has been proposed that miRNAs may be crucial to the modulation of the function of semaphorins. Previous findings have proven that miR-497-5p is upregula...
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