Neda Soleimani
Department of Microbiology, Faculty of Biological Sciences, Shahid Beheshti University, Tehran, Iran
[ 1 ] - Preparation and Evaluation anticancer activity of D-glucosamine Nanoparticles on Metastatic cancer Model in vivo
Objective(s): Breast cancer imposes a highest rate of malignancy among the women all around the world. Chitin and its derivatives such as D-glucosamine-carboxymethyl chitin and Di-hydroxy propyl chitin have immune-modulating effects and influence on innate and acquisitive immunity which lead to cell activity enhancement. The aim of this study was investigating the effect ...
[ 2 ] - ارزیابی فعالیت سیتوتوکسیسیتی عصاره سلولی میکروارگانیسم های کفیر بر روی رده سلولهای سرطانی گلیوبلاستوما
Background & Aims: Kefir is a complex composition of microbial species such as streptococci, mesophilic lactobacilli, lactose or non-lactose fermenting yeast and acetic acid bacteria. Numerous studies have been performed to indicate the positive therapeutic effect and healing properties of probiotic products. The aim of this study was to investigate the effect of cytotoxicity of kefir microorga...
[ 3 ] - Evaluation of proliferation and survival of spleen immune cells treated by Deacetylchitin nanoparticles on breast cancer mouse model
Background & Aims: Breast cancer is the most common carcinoma in women and one of the main causes of death in developed and developing countries. Today, compounds with immunolodulator properties can be replaced with routine drugs. One of them is Deacetylchitin. This study aimed to evaluate proliferation and survival of spleen immune cells treated by Deacetylchitin nanoparticles on breast c...
[ 4 ] - اثرات ایمونولوژیکی نانوذرات کیتوزان بر سلولهای سرطانی سینه در مدل حیوانی
زمینه و هدف: سرطان از علل عمده مرگ و میر در سراسر جهان است. درمانهای دارویی، متعارف با استفاده از داروهای سیتوتوکسیک دارای سطح بالایی از عوارض جانبی برای بیمار هستند. کیتوزان یک ترکیب زیست سازگار و زیست تخریب‌پذیر می‌باشد. بنابراین، با توجه به حداقل مسمومیت سیستمیک برای تحویل پپتید یا دارو، در برنامه‌های کاربردی مطرح است. در این مطالعه اثرات ایمونولوژیکی نانوذرات کیتوزان بر سلولهای سرطانی سین...
[ 5 ] - نقش هلیکوباکتر پیلوری در ایجاد سرطان معده و کاربردهای بالینی آن در درمان سر طان‌ها
The repeated exposure of a normal cell to carcinogenic agents may lead to its mutation, which changes into a cancer cell. In this case, the structure and function of the cells would alter, and they do not act normally. Chemicals, sun exposure, shortwaves, viruses, and bacteria play a significant role in cancer. Among the infectious and bacterial agents causing cancer, Helicobacter pylori (H. py...
[ 6 ] - آماده‌سازی نانوذرات تری‌متیل کیتوزان حامل پروتئین فعال کننده نوتروفیلی نوترکیب از هلیکوباکتر پیلوری
Background and purpose: Breast cancer is one of the leading causes of death in women around the world with a very high degree of mortality and morbidity. Conventional treatments use cytotoxic drugs which have high levels of side effects, affecting the patient’s quality of life. Therefore today’s pharmacology is looking into treatments with low side effects and maximum efficiency. The helicobact...
[ 7 ] - شناسایی بیوآئروسل‌های باکتریایی در ایستگاه‌های پرستاری یک بیمارستان دولتی در شهر تهران
Background and Objective: Bacterial exposure in hospitals due to the presence of pathogens in hospitals is one of important health problems for medical staff. The World Health Organization (WHO) reported a global outbreak of hospital infections from 5.7% to 19.1% in the 2011 report. The aim of this study was to identify bacterial bioaerosols in nursing stations in a public hospital in Tehran to...
[ 8 ] - بیان ژنVEGF و MMp9 در اثر تیمار با پروتئین نوترکیب فعال کننده نوتروفیلی هلیکوباکترپیلوری بر مدل سرطان پستان
سابقه و هدف: سرطان پستان از علل عمده مرگ و میر زنان در سراسر جهان است. درمانهای دارویی سیتوتوکسیک دارای سطح بالایی از عوارض جانبی برای بیمار می باشد. پروتئین نوترکیب فعال کننده نوتروفیلی هلیکوباکترپیلوری (HP-NapA)، یکی از مهمترین پروتئینهای ترشحی هلیکوباکترپیلوری است. هدف از این مطالعه بررسی بیان ژن VEGF و MMp9 در اثر تیمار با پروتئین نوترکیب فعال کننده نوتروفیلی هلیکوباکترپیلوری بر مدل متاستا...
[ 9 ] - Anti -Bacterial Activity of Punica granatum Flower Extract against Several Gram-Negative and Positive Bacteria
Background and objectives: Bacterial antibiotic resistance is a major issue in the process of infectious disease treatments. The aim of this study was an evaluation of the antibacterial activity of Punica granatum flower extract against several gram-negative and positive clinical bacterial isolates. Methods: An adequate dried flower of an endemic mature Punica granatum plant was used for ex...
[ 10 ] - A Review of Designing New Vaccines to Prevent Hospital-Acquired Antibiotic-Resistant Infections
Hospital-acquired infections are one of the main challenges and concerns of patients and medical staff in hospitals and healthcare centers. Meanwhile, Clostridium difficile infection is one of the most important bacterial hospital infections. Prevention is the best and most effective way to deal with these infections. Designing and using vaccines against these infectious microorganisms is the b...