Bahman Khameneh

Biotechnology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran|Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran

[ 1 ] - Combined effects of PEGylation and particle size on uptake of PLGA particles by macrophage cells

Objective:At the present study, relationship between phagocytosis of PLGA particles and combined effects of particle size and surface PEGylation was investigated.  Materials and Methods:Microspheres and nanospheres (3500 nm and 700 nm) were prepared from three types of PLGA polymers (non-PEGylated and PEGylation percents of 9% and 15%). These particles were prepared by solvent evaporation metho...

[ 2 ] - In vivo evaluation of mucoadhesive properties of nanoliposomal formulations upon coating with trimethylchitosan polymer

Objective(s): Drug delivery via mucosal routes has been confirmed to be effective in inducing strong immune responses. Liposomes could enhance immune responses and mucoadhesive potentials, make them useful mucosal drug delivery systems. Coating of liposomes by mucoadhesive polymers succeeded in enhancing immune responses. Our studies aim at preparation and characterization of trimethylchitosan-...

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