Atefeh Pooryasin
Department of Genetics, College of Sciences, Shahid Chamran University, Ahvaz 61357-44337, Iran
[ 1 ] - Additive effect of MTHFR and GRIN1 genetic polymorphisms on the risk of schizophrenia
Schizophrenia is a complex disorder with polygenic inheritance. The MTHFR gene (OMIM: 607093) plays an important role in the folate metabolism. It has been suggested that C677T (rs1801133) and A1298C (rs1801131) genetic polymorphisms in the MTHFR gene lead to the decreased activity of the methylenetetrahydrofolate reductase enzyme which may have significant effect on developing schizophrenia. W...
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