Hamid Mobasheri

Laboratory of Membrane Biophysics, Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran

[ 1 ] - Impact of heat shock step on bacterial transformation efficiency

CaCl2 treatment followed by heat shock is the most common method for artificial transformation. Here, the cells were transformed using CaCl2 treatment either with heat shock (standard protocol) or without heat shock (lab protocol) to comprehend the difference in transformation efficiency. The BL21 strain of Escherichia coli (E. coli) was being susceptible using CaCl2 treatment. Some Cells were ...

[ 2 ] - Polyethylene Glycol Repairs Damaged Membrane; Biophysical Application of Artificial Planar Bilayer to Mimic Biological Membrane

Polyethylene glycol (PEG) is a hydrophilic polymer, known to be capable to fuse numerous single cells in vitro, to join the membranes of adjacent neurons and giant invertebrate axons, and to seal damaged neural membranes. The molecular mechanism of the action of PEG is still unknown. It is believed that PEG dehydrates membranes and enables their structural components to resolve and rearrange in...

[ 3 ] - تأثیر میدان مغناطیسی ایستا بر فعالیت سلول​ها در مدل آزمایشگاهی آسیب نخاعی

هدف: آسیب نخاعی سالانه زندگی میلیون​ها نفر از مردم جهان را با ایجاد اثر​های طولانی​مدت و ماندگار در طول عمر ایشان تغییر می​دهد. هدف اصلی تحقیقات بیوفیزیکی در سطوح سلولی و مولکولی در حیطۀ آسیب​های نخاعی، بهبود روش​های ترمیم نخاع با حداقل عوارض جانبی است. استفاده از میدان مغناطیسی ایستا (SMF) به​عنوان یک روش درمانی غیرتهاجمی، ارزان و از راه دور می​تواند یکی از رویکردهای امیدوار​کننده باشد. هدف ا...

[ 4 ] - Effects of Biodegradable Polymers on the Rat's Damaged Spinal Cord Neural Membranes

     The overall goal of this study was to identify the appropriate biomaterials able to facilitate the regeneration in rat's injured adult spinal cord. Acute damage to axons is manifested as a breach in their membranes, ionexchange distortion across the compromised region, local depolarization and even conduction block. It would be of particular importance to interrupt the progress of events h...