Seyed Noureddin Nematollahi-Mahani
Professor, Department of Anatomy, Afzalipour School of Medicine & Physiology Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Sciences, Kerman, Iran
[ 1 ] - Effect of Chondroitinase ABC Enzyme on Glial Fibrillary Acidic Protein, Chondroitin Sulfated Proteoglycans and Chondroitin 4-Sulfate Levels in an Animal Model of Spinal Cord Injury
Background: Following spinal cord injury, reactive astrocytes upregulate chondroitin sulfate proteoglycans (CSPGs) which act as a barrier to neuronal repair and regeneration. Therefore, enzymatic digestion of CSPGs by chondroitinase ABC (cABC) is a key strategy in the treatment of spinal cord injury. Furthermore, cABC has been shown to attenuate post spinal cord injury inflamma...
[ 2 ] - Assess The Pluripotency of Caprine Umbilical Cord Wharton’s Jelly Mesenchymal Cells By RT-PCR Analysis of Early Transcription Factor Nanog
Objective- In the present study we investigated the isolation protocol, population doubling time (PDT) and the expression of a pluripotential gene by RT-PCR analysis of early transcription factor Nanog in caprine umbilical cord (CUC) Wharton's jelly mesenchymal cells (WJMCs). Design- Experimental in vitro study. Animals- Four mix breed goat. Procedures- CUCs were collected from abattoi...
[ 3 ] - The effect of chronic administration of morphine on end stages of oocyte meiosis and in vitro fertilization in Syrian mice
substances can effect on the Hypothalamus-hypophysis-ovary and affect the performance of the Addictive substances can affect the reproductive system and they affect the secretion of gonadotropins. Morphine significantly reduces plasma LH levels in all range groups of men and women. Most illicit drugs and opioids, including morphine, are associated with decreased physical stimulat...
[ 4 ] - The Regression of Glioblastoma Multiforme is Time Dependent in Wild-Type Rat Xenograft Model
Introduction: Glioblastoma multiforme (GBM) is an aggressive case of primary brain cancer which remains among the most fatal tumors worldwide. Although, some in vitro and in vivo models have been developed for a better understanding of GBM behavior; a natural model of GBM would improve the efficiency of experimental models to human GBM tumors. We aimed at the present study to examine the surviv...