Iraj Mirzaii-Dizgah
Full Prof. of Department of Physiology, School of Medicine, Aja University of Medical Sciences, Tehran, Iran
[ 1 ] - Vascular Endothelial Growth Factor in Serum and Saliva of Oral Lichen Planus and Oral Squamous Cell Carcinoma Patients
Background:Oral lichen planus (OLP) is considered as a potentially malignant disorder and vascular endothelial growth factor (VEGF) may play a key role in cancer development. The aim of this study was to compare serum and saliva VEGF among patients with OLP, oral squamous cell carcinoma (OSCC) and a healthy control group. Methods:A cross sectional study was pe...
[ 2 ] - بررسی میزان آنتی‌اکسیدان عصاره حاصل از مغز، پوست نرم و پوست سخت بادام زمینی
مقدمه: در سال‌های اخیر تمایل زیادی به مصرف مکمل‌های تغذیه‌ای آنتی‌اکسیدانی جهت مهار اثرات مخرب استرس‌های اکسیداتیو به‌وجود آمده است. لذا در این مطالعه، میزان فنول تام، ظرفیت آنتی‌اکسیدان تام و فعالیت پاکسازی رادیکال‌های آزاد عصاره متانولی مغز و پوسته‌های سخت و نرم بادام زمینی مورد بررسی قرار گرفت. روش بررسی: برای سنجش میزان فنول تام، ظرفیت آنتی‌اکسیدان تام و فعالیت پاکسازی رادیکال‌های آزاد ...
[ 3 ] - Reduction of Saliva and Serum 25-Hydroxycholecalciferol in Multiple Sclerosis
Methods: The prevalence of multiple sclerosis (MS) is high in patients suffering from 25-hydroxyvitamin D3 [25(OH)D] deficiency. The aim of this study was to investigate the possible association of saliva and serum 25(OH)D concentrations with MS in women.Methods: Serum and saliva 25(OH)D levels of 30 MS women and 30 matched healthy controls in this case-control study were measured by ELIS...
[ 4 ] - The Evaluation of the Level of C3 and C4 Complements in Unstimulated Saliva of Patients with Oral Lichen Planus
Background and Objectives: Deficiency in the complement system can lead to some autoimmune diseases, such as systemic lupus erythematosus. The purpose of this study was to investigate the levels of C3 and C4 complements in unstimulated saliva of individuals with oral lichen planus (OLP) and healthy subjects. Methods: In this case-control study, 31 healthy individuals and 31 patients with OLP en...
[ 5 ] - Serum and Saliva Myelin Basic Protein as Multiple Sclerosis Biomarker
Objective: Multiple sclerosis (MS) is presented with motor and sensory function loss. It is caused by demyelination and following axonal lesion. As myelin basic protein (MBP) is one of the key elements of the myelin cover, we examined the level of MBP in serum, stimulated, and unstimulated saliva as a suitable biomarker for detecting MS. Methods: A case-control study was performed in 29 health...
[ 6 ] - The effect of simulated weightlessness and short-term light-dark cycle on retinoic acid levels in serum and hippocampus of rats
Background: spacecrafts rotate around the Earth every 90 minutes, so the 24-hour cycle turns to 90 minutes. Retinoic acid, an active metabolite of vitamin A, plays a role in regulating the circadian rhythm and its deficiency can impair the biological clock function and consequently impair the circadian rhythm of locomotor activity. The goal of the study was to assay the effects of simulated spa...
[ 7 ] - Cardiovascular Effect of Dorsal Periaqueductal Gray During Lipopolysaccharide-induced Hypotension
Introduction: The central mechanism related to the cardiovascular response to lipopolysaccharide (LPS)-induced hypotension is not entirely known, but it is suggested that numerous brain areas such as dorsal periaqueductal gray (dPAG) are involved in this process. In the current work, the cardiovascular effect of the dPAG during LPS-induced hypotension is investigated. Methods: The study animal...
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