Fariba Ansari
Shahed University
[ 1 ] - The effect of methadone and haloperidol combination on anxiety induced by morphine withdrawal in male mice
Background and Objective: Regarding inefficiency of common drugs used for alleviation of anxiety due to narcotics withdrawal, the present study was evaluated methadone and haloperidol co-drugs therapy on anxiety due to morphine withdrawal. Materials and Methods: Ninety eight NMRI male mice were divided into acute and chronic experimental groups. Then, each group was divided into 7 subgroups: sa...
[ 2 ] - The effect of silymarin on prevention of hippocampus neuronal damage in rats with temporal lob epilepsy
Background and Objective: Temporal lobe epilepsy is hallmarked with neuronal degeneration in some areas of hippocampus and mossy fiber sprouting in dentate area. Considering some evidences on neuroprotective and antioxidant activity of silymarin (SM), this study was undertaken to evaluate the preventive effect of this agent on structural changes in hippocampus of kainate-epileptic rats. Materia...
[ 3 ] - Dose-dependent effect of Hypericum perforatum extract on motor imbalance following intrastriatal injection of 6-hydroxydopamine in the rat
Background and Objective: Parkinson's disease (PD) is a neurodegenerative disease with selective damage of mesencephalic dopaminergic neurons. Due to the protective, anti-inflammatory, and antioxidant effect of Hypericum perforatum (HP), this study was undertaken to assess dose-dependent effect of HP hydroalcoholic extract on motor imbalance following intrastriatal injection of 6-hydroxydopamin...
[ 4 ] - Antinociceptive Effect of Oral and Intraperitoneal Administration of Alcoholic Viscum Album Fruit Extract in Male Rats
Objective: The present study was designed to investigate the analgesic effect of oral and i.p. administration of alcoholic Viscum album (V.A) fruit extract as a rich source of alkaloid substances. Materials and Methods: Experimented animals were divided into control and treatment groups. The treatment rats received different doses of the V.A fruit extract, which was prepared from alcoholic sma...
[ 5 ] - A comparison of acute pain thresholds between the male and female and the effect of alcoholic Datura stramonium seed extract on it
Introduction: Opposite observations about the discrepancy in the pain perception between male and female has been reported. In this regard, pain thresholds among male and female rats in different phases of oestrous cycle were evaluated via tail immersion test. In addition, efficiency of alcoholic extract of datura stramonium as an analgesic plant in the modulation of acute pain threshold has be...