Ashkan Sanaie Rad
Department of Physiology, School of Medicine, Shahed University Tehran, Iran
[ 1 ] - Ameliorative activity of co-administration of ketamine and ECT on depression like behaviors in depressed rats
Background and Objective: Electroconvulsive therapy (ECT) is the end choice treatment for patients with major depressive disorder (MDD). Regarding researches that show NMDA receptor inactivation could yield the same results as anti-depressant drugs, however, the present study examined co-administration of ECT and ketamine (as NMDA antagonist) on depressed rat behaviors. Materials and Methods...
[ 2 ] - The effect of methadone and haloperidol combination on anxiety induced by morphine withdrawal in male mice
Background and Objective: Regarding inefficiency of common drugs used for alleviation of anxiety due to narcotics withdrawal, the present study was evaluated methadone and haloperidol co-drugs therapy on anxiety due to morphine withdrawal. Materials and Methods: Ninety eight NMRI male mice were divided into acute and chronic experimental groups. Then, each group was divided into 7 subgroups: sa...
[ 3 ] - The effect of electroconvulsive therapy on the levels of oxidative stress factors in the prefrontal cortex of depressed rats
Background and Objective: Electroconvulsive therapy (ECT) is one of the effective and less complicated methods for treatment of depression in cases of resistance to common treatments. Given the fundamental role of pre-frontal cortex on changing the mood of depression-related behaviors in depressed patients, the effects of electroconvulsive therapy on enzymatic activity of this cortex were taken...
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