Alireza Tavangar Ranjbar
Department of Virology, Tehran University of Medical Sciences, Tehran, Iran
[ 1 ] - Use of N-trimethyl chitosan for intranasal delivery of DNA encoding M2e-HSP70c in mice
BACKGROUND: Influenza outbreak has become a great lifethreateningdisease in the world. Nasal vaccines can inducesystemic IgG and mucosal IgA antibody responses, whichestablish two layers of immune defense against the infectiouspathogens like influenza. Mucosal vaccines must overcomeseveral limitations, including the mucociliary clearance andinefficient uptake of soluble antigens. Therefore, nas...
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