Jafar Akbari
Department of Pharmaceutics, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran.
[ 1 ] - Enhancement of Dissolution Rate of Indomethacin Using Liquisolid Compacts
The potential of liquisolid systems to improve the dissolution properties of a water-insoluble agent (indomethacin) was the purpose of this survey. In this study, different formulations of liquisolid tablets using different co-solvents (non-volatile solvents) were prepared and the effect of several amounts of them on the dissolution behaviour of indomethacin was investigated. It is worth mentio...
[ 2 ] - Enhancement of Dissolution Rate of Indomethacin Using Liquisolid Compacts
The potential of liquisolid systems to improve the dissolution properties of a water-insoluble agent (indomethacin) was the purpose of this survey. In this study, different formulations of liquisolid tablets using different co-solvents (non-volatile solvents) were prepared and the effect of several amounts of them on the dissolution behaviour of indomethacin was investigated. It is worth mentio...
[ 3 ] - بررسی تأثیر نوع و مقدار پلیمر بر قدرت مخاط چسبی و سرعت آزادسازی دارو از فیلم های مخاط چسب داخل گونه ای دیکلوفناک سدیم
Background and purpose: Buccal delivery of drug provides an attractive alternative to the oral route of drug administration and a convenient route of administration for both systemic and local drug delivery. Absorption of therapeutic agents from the oral cavity provides a direct entry for such agents into the systemic circulation, thereby avoiding first-pass metabolism and gastrointestinal d...
[ 4 ] - بررسی پایداری فیزیکی حالت جامد و سازگاری پیروکسیکام با مواد جانبی قرص‌ها توسط روش‌های فیزیکوشیمیایی
Background and purpose: The pharmaceutical excipients can be incompatible with drug or other excipients. Thus, for each material, compatibility with formulation components and packaging materials should be examined. The dissolution of a drug has an important role in its bioavailability. Any change in the physico-chemical properties can result in changes in the drug release, and furthermore in i...
[ 5 ] - بررسی تأثیر اعمال حرارت بر کنترل سرعت آزادسازی تئوفیلین از ماتریس‌های حاوی پلیمرهای اودراجیت RS و M4K HPMC با استفاده از روش مایع به جامد
Background and purpose: The potential of liquisolid systems for increasing drug dissolution has been proved in many researches. Recent studies have shown that liquisolid technique is a new and promising method for controlling the dissolution rate of drugs. Based on thermal treating effect on polymer structure, in this study the effects of thermal treating on theophylline release from liquisolid...
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