Behrooz Alirezapour
Agricultural, Medical and Industrial Research School (AMIRS), Nuclear Science and Technology Research Institute, Rajaeeshahr, Karaj, Iran, P.O.Box: 31485-498.
[ 1 ] - Production and Quality Control of [67Ga]-DOTA-trastuzumab for Radioimmunoscintigraphy
Breast cancer radioimmunoscintigraphy targeting HER2/neu expression is a growing fieldof work in nuclear medicine research. In this study, trastuzumab was successively labeledwith [67Ga] GaCl3 after conjugation with DOTA-NHS-ester.The conjugates were purified by molecular filtration, the average number ofDOTA conjugated per mAb was calculated and total concentration was determined byspectrophot...
[ 2 ] - Production and Quality Control of [67Ga]-DOTA-trastuzumab for Radioimmunoscintigraphy
Breast cancer radioimmunoscintigraphy targeting HER2/neu expression is a growing fieldof work in nuclear medicine research. In this study, trastuzumab was successively labeledwith [67Ga] GaCl3 after conjugation with DOTA-NHS-ester.The conjugates were purified by molecular filtration, the average number ofDOTA conjugated per mAb was calculated and total concentration was determined byspectrophot...
Co-Authors