Kamyar Pourghazi

[ 1 ] - HPTLC-Densitometric Determination of Cetirizine and Montelukast Analysis in Combined Tablet Dosage Forms

A simple, accurate and rapid high performance thin layer chromatography (HPTLC)-densitometric method was developed for separation and determination of cetirizine (CET) as a long acting antihistamine and montelukast (MON) as an antileukotriene in pharmaceutical dosage forms. The compounds were separated on silica gel 60 F254 HPTLC plates using a mixture of ethyl acetate : methanol : ammonia solu...

[ 2 ] - Core-shell magnetic pH-responsive vehicle for delivery of poorly water-soluble rosuvastatin

Objective(s): Development of an oral sustained-controlled release vehicle which, slowly releases the drug and maintains an effective drug concentration for a long time is aimed.Materials and Methods: A biodegradable magnetic polymeric drug delivery vehicle, using superparamagnetic iron oxide nanoparticles encapsulating by polyvinylpyrrolidone-block-polyethylene glycol-block-poly methacrylic aci...

[ 3 ] - Poly (methacrylic acid-co-acrylic acid)-grafted polyvinylpyrrolidone coated Magnetic nanoparticles as a pH-responsive magnetic Nano-carrier for controlled delivery of antibiotics

Objective(s): Pharmaceutical industries are leading to improved medications that can target diseases more effectively and precisely. Researchers have intended to reformulate drugs so that they may be more safely used in human body. The more targeted a drug is, the lower its chance of triggering drug resistance, a cautionary concern surrounding the use of broad-spectrum antibiotics. The aim of t...

[ 4 ] - CoFe2O4 nanoparticles grafted multi-walled carbon nanotubes coupled with surfactant-enhanced spectroﬂuorimetry for determination of oﬂoxacin in human plasma

An efficient and simple magnetic solid phase extraction based on the use of CoFe3O4 nanoparticles grafted multi-walled carbon nanotubes (MWCNTs) as adsorbent coupled with surfactant enhanced spectroﬂuorimetric detection...

[ 5 ] - Gold nanoparticles grafted manganese doped Fe3O4 nanoparticles for determination of short-term release of silver and lead from dental amalgam in saliva

Ethylene glycol bisthioglycolate modified gold nanoparticles grafted Mn doped Fe3O4 nanoparticles (Au@Mn-Fe3O4 NPs) adsorbent was synthesized and applied for extraction and preconcentration of trace amounts of Ag+ and Pb2+ ions in artificial and natural saliva. The adsorbent was characterized by transmission electron microscopy (...

[ 6 ] - Extraction, preconcentration and spectrometric determination of Al (III) and Cr (III) ions using modified MnFe2O4 nanoparticles as an efficient adsorbent

An efficient and reusable adsorbent, namely 3-mercaptopropionic acid modified tetraethyl orthosilicate (TEOS) grafted MnFe2O4 nanoparticles (MPA-TEOS-MnFe2O4 NPs) was synthesized and used for the extraction and preconcentration of trace amount of Al (III) and Cr (III) ions in water samples. MnFe2O4 NPs were prepared by chemical c...

[ 7 ] - Dispersive liquid-liquid microextraction coupled with magnetic nanoparticles for extraction of zearalenone in wheat samples

A new, sensitive and fast dispersive liquid-liquid microextraction (DLLME) coupled with micro-solid phase extraction (μ-SPE) was developed for determination of zearalenone (ZEN) in wheat samples. The DLLME was performed using acetonitrile/water (80:20 v/v) as the disperser solvent and 1-octanol as the extracting solvent. The acetonitrile/water (80:20 v/v) solvent was also used to extract ZEN f...

[ 8 ] - Magnetic nanoparticles grafted pH-responsive poly (methacrylic acid-co-acrylic acid)-grafted polyvinylpyrrolidone as a nano-carrier for oral controlled delivery of atorvastatin

Objective(s): Researchers have intended to reformulate drugs so that they may be more safely used in human body. Polymer science and nanotechnology have great roles in this field. The aim of this paper is to introduce an efficient drug delivery vehicle which can perform both targeted and controlled antibiotic release using magnetic nanoparticles grafted pH-responsive polymer.<s...

[ 9 ] - HPTLC-Densitometric Determination of Cetirizine and Montelukast Analysis in Combined Tablet Dosage Forms

A simple, accurate and rapid high performance thin layer chromatography (HPTLC)-densitometric method was developed for separation and determination of cetirizine (CET) as a long acting antihistamine and montelukast (MON) as an antileukotriene in pharmaceutical dosage forms. The compounds were separated on silica gel 60 F254 HPTLC plates using a mixture of ethyl acetate : methanol : ammonia solu...

[ 10 ] - Thiol modified Au nanoparticles grafted manganese doped magnetic iron oxide nanoparticles for spectrometric determination of short-term release of mercury and copper from dental amalgam in saliva

Abstract A new adsorbent, ethylene glycol bisthioglycolate modified gold nanoparticles grafted Mn doped Fe3O4 nanoparticles (EGBTG-Au@Mn-Fe3O4 NPs) were synthesized through chemical precipitation followed by an oxidative Mn doping process to use for extraction and preconcentration of trace amounts of Hg, and Cu ions in artificial and natural saliva. The prepared adsorbent was characterize...

[ 11 ] - Use of laser-triggered gold nanoparticle-grafted dual light and temperature-responsive polymeric sensor for the recognition of thioguanine as anti-tumor agent

Objective(s): Today, there is an urgent need for improved sensor materials for drug sensing and effective monitoring and interventions in this area are highly required to struggle drug abuse. The present study aimed to synthesize a thioguanine-responsive sensor based on a nanocomposite consisting of AuNP-grafted light- and temperature-responsive poly butylmethacrylate-co-acrylamide-co-methacryl...