Farshad Roghani Dehkordi

[ 1 ] - Endothelium-dependent Effect of Sesame Seed Feeding on Vascular Reactivity of Streptozotocin-diabetic Rats: Underlying Mechanisms

Cardiovascular disorders continue to constitute major causes of morbidity and mortality in diabetic patients. In this study, the effect of chronic administration of sesame (Sesamum indicum L) seed feeding was studied on aortic reactivity of streptozotocin (STZ)-diabetic rats. Male diabetic rats received sesame seed-mixed food at weight ratios of 3% and 6% for 7 weeks, one week after diabetes in...

[ 2 ] - The Effect of Hepatocyte Growth Factor on Learning and Memory Abilities in a Rat Model of Kainate-Induced Epilepsy

Background and Objective: Epilepsy as a chronic neurological disorder causes inherent seizures and learning and memory failure. Since there is no acceptable control of seizures in some patients with the current recommended drug therapy, new medications with different mechanisms of action are needed. Here, the beneficial effect of hepatocyte growth factor (HGF) was evaluated in an experimental m...

[ 3 ] - The effects of aqueous cinnamon bark extract and cinnamaldehyde on neurons of substantia nigra and behavioral impairment in a mouse model of Parkinson’s disease

Background and Objective: Parkinson's disease (PD) is characterized by a progressive loss of dopaminergic neurons in substantia nigra. In recent years, there have been interests in the role of the free radical damage in PD. Cinnamon and its derivative, cinnamaldehyde acts as powerful antioxidant and anti-inflammatory agents. This research focused on the effects of cinnamon extract and cinnamald...

[ 4 ] - Antinociceptive activity of Tribulus terrestris oral feeding in diabetic rats: Involvement of lipid peroxidation

Background and Objective: Due to the presence of some evidence for anti-diabetic and antioxidant activity of Tribulus terrestris (TT), this study was designed to investigate the anti-nociceptive effect of TT in streptozotocin-diabetic rats using formalin test and hot tail immersion tests. Materials and Methods: Rats were divided into control, TT-treated control, diabetic, sodium salicylate (SS)...

[ 5 ] - Association of Inflammatory Mediators with Coronary Artery Disease in Diabetic Patients

Background and Objectives: Coronary artery disease (CAD) is regarded as the leading cause of morbidity and mortality around the world. Diabetes mellitus (DM) is associated with the development of CAD and increased risk of morbidity and mortality. The goal of this study was to assess the association of tumor necrosis factorα (TNF-α) and high sensitivity C-reactive protein (hsCRP) with CAD severi...

[ 6 ] - The in vitro effect of Melissa officinalis aqueous extract on aortic reactivity in rats with subchronic diabetes

Abstract Background and Objective: Vascular abnormality and dysfunction plays an important role in the pathogenesis of vascular disease in diabetic state. In this study, we aimed to investigate whether an in vitro exposure of endothelium-intact aortic rings to Melissa officinalis (lemon balm, MO) aqueous extract could have a beneficial effect in rats with subchronic diabetes. Materials and Meth...

[ 7 ] - Endothelium-dependent Effect of Sesame Seed Feeding on Vascular Reactivity of Streptozotocin-diabetic Rats: Underlying Mechanisms

Cardiovascular disorders continue to constitute major causes of morbidity and mortality in diabetic patients. In this study, the effect of chronic administration of sesame (Sesamum indicum L) seed feeding was studied on aortic reactivity of streptozotocin (STZ)-diabetic rats. Male diabetic rats received sesame seed-mixed food at weight ratios of 3% and 6% for 7 weeks, one week after diabetes in...

[ 8 ] - A comparative review of various interventional methods for coronary angiography and angioplasty

Background and Objective: Coronary artery disease (CAD) is one of the most common diseases today. Among the diagnostic methods, angiography is the main and gold standard in the diagnosis Since angiography is an invasive procedure, this procedure complications range widely from minor problems with short term sequelae to life threatening ones may cause irreversible damage or even death. Materials...