Heidar Tavilani Tavilani
Department of Biochemistry, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
[ 1 ] - Propofol Attenuates Toxic Oxidative Stress by CCl4 in Liver Mitochondria and Blood in Rat
Anti-oxidant effects of propofol (2, 6-diisopropylphenol) were evaluated agains carbon tetrachloridet CCl4 -induced oxidative stress in rat liver. 30 male rats were equally divided in to 6 groups (5 rats each). Group I (control), while Group II was given CCl4 (3 mL /Kg/day, IP). Animals of Groups III received only propofol (10 mg/Kg/day, IP). Group IV was given propofol+ CCl4. Group V was admin...
[ 2 ] - Propofol Attenuates Toxic Oxidative Stress by CCl4 in Liver Mitochondria and Blood in Rat
Anti-oxidant effects of propofol (2, 6-diisopropylphenol) were evaluated agains carbon tetrachloridet CCl4 -induced oxidative stress in rat liver. 30 male rats were equally divided in to 6 groups (5 rats each). Group I (control), while Group II was given CCl4 (3 mL /Kg/day, IP). Animals of Groups III received only propofol (10 mg/Kg/day, IP). Group IV was given propofol+ CCl4. Group V was admin...
[ 3 ] - Genistein Induces Apoptosis and Inhibits Proliferation of HT29 Colon Cancer Cells
Soybean isoflavone genistein has multiple anticancer properties and its pro-apoptotic and anti-proliferative effects have been studied in different cancer cells. However, the mechanisms of action of genistein and its molecular targets on human colon cells have not been fully elucidated. Therefore, caspase-3 and p38 mitogen-activated protein kinase (p38 MAPK) as the main therapeutic targets...
[ 4 ] - بررسی اثر سیلی مارین بر بیان ژن های اوروتنسین 2 و گیرنده آن در بافت کبد رتهای دیابتی تیپ 2
سابقه و هدف: مطالعات نشان میدهند که افزایش U-IIبا اختلالات دیابت مرتبط میباشد. با توجه به اینکه داروهای گیاهی برای درمان بیماری نسبت به بسیاری از داروهای شیمیایی عوارض کمتری دارند، در این مطالعه اثر سیلیمارین بر سطوح گلوکز، انسولین و بیان ژنهایU-II و گیرنده اوروتنسین2 (U-II R) در رتهای نر دیابتی تیپ2 مورد بررسی قرار گرفت. مواد و روش ها: در این مطالعه تجربی 36رت نر ویستار آلبینو به‌صورت ت...
[ 5 ] - Kiwifruit effect on adipose tissue cell size and cholesteryl ester transfer protein gene expression in high-fat diet fed Golden Syrian hamsters
Objective: The effects of kiwifruit on the histology and cell size of adipose tissue in hyperlipidemic models have not yet been reported. Therefore, this study aimed to investigate the effect of kiwifruit on the adipose tissue cell size and activity as well as the gene expression of cholesteryl ester transfer protein (CETP) in high-fat diet (HFD...
[ 6 ] - Hepatoprotective Effects of Silymarin on Liver Injury via Irisin Upregulation and Oxidative Stress Reduction in Rats with Type 2 Diabetes
Background: Diabetes is one of the most prevalent metabolic diseases. Irisin (FNDC5 protein) is involved in the new strategy of combating type 2 diabetes. In the liver, the antidiabetic mechanism of silymarin at the molecular level is unknown. This study investigated the effects of silymarin on irisin and the related gene expression and oxidative stress status in the liver of type 2 diabetic ra...
[ 7 ] - Aqueous Extract of Anethum Graveolens L. has Potential Antioxidant and Antiglycation Effects
The aim of this study was to assess the antiglycation and antioxidant properties of aqueous extract of Anethum graveolens (dill). In the in vivo and in vitro experiments, antioxidant properties, blood glucose, and AGEs formation were determined. Dill extract was given orally to healthy and diabetic rats. Our results illustrated that different concentrations of dill extract (0.125, 0.25, 0.5, an...
[ 8 ] - Gene Polymorphism of Matrix Metalloproteinase 9 in Asthenozoospermic Male Subjects
Objective Matrix Metalloproteinase (MMPs) play important roles in the structural and functional properties of reproductive organs. The aim of this study is to determine the prevalence of C-1562T Matrix Metalloproteinase-9 (rs3918242) gene polymorphism in fertile and infertile men. In addition, we aimed to determine the association between C-1562T MMP-9 and G-1575A MMP-2 gene polymorphisms. Mate...
[ 9 ] - P-115: The Role of G22A Adenosine Deaminase 1 Gene Polymorphism and The Activities of ADA Isoenzymes in Fertile and Infertile Men
Background Some studies have revealed enzymatic and non-enzymatic roles of adenosine deaminase (ADA) in male reproductive system such as regulating adenylate cyclase activity by decreasing adenosine concentration, helping to interaction between prostasomes and spermatozoa. MaterialsAndMethods frequency distribution of ADA1 G22A alleles and genotypes in 200 fertile and 200 infertile men. The pol...
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