Majid Saeedi
Department of Pharmaceutics, School of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran
[ 1 ] - Correlation Between Sun Protection Factor and Antioxidant Activity, Phenol and Flavonoid Contents of Some Medicinal Plants
Long exposure of UV radiation increases risk of skin diseases such as cancer and photoallergic reactions. UV-B (280-320 nm) radiation is mainly responsible for inducing skin problems. Skin protection is a suitable method in the fight against ultraviolet radiation induced damage. Various synthetic agents have been used as photo protective but because of their potential toxicity in humans, they h...
[ 2 ] - Enhancement of Dissolution Rate of Indomethacin Using Liquisolid Compacts
The potential of liquisolid systems to improve the dissolution properties of a water-insoluble agent (indomethacin) was the purpose of this survey. In this study, different formulations of liquisolid tablets using different co-solvents (non-volatile solvents) were prepared and the effect of several amounts of them on the dissolution behaviour of indomethacin was investigated. It is worth mentio...
[ 3 ] - Correlation Between Sun Protection Factor and Antioxidant Activity, Phenol and Flavonoid Contents of Some Medicinal Plants
Long exposure of UV radiation increases risk of skin diseases such as cancer and photoallergic reactions. UV-B (280-320 nm) radiation is mainly responsible for inducing skin problems. Skin protection is a suitable method in the fight against ultraviolet radiation induced damage. Various synthetic agents have been used as photo protective but because of their potential toxicity in humans, they h...
[ 4 ] - Enhancement of Dissolution Rate of Indomethacin Using Liquisolid Compacts
The potential of liquisolid systems to improve the dissolution properties of a water-insoluble agent (indomethacin) was the purpose of this survey. In this study, different formulations of liquisolid tablets using different co-solvents (non-volatile solvents) were prepared and the effect of several amounts of them on the dissolution behaviour of indomethacin was investigated. It is worth mentio...
[ 5 ] - مروری بر فرآوردهفرآورده های گیاهی دهان و دندان
Oral hygiene products have been used widely among people since many years ago. Toothpaste and mouthwashes are the main products that are used for health and beauty and the demand for such dental products is high. These products include both chemical and herbal products. Plants form a large part of the surrounding nature, so they are the first choice for health problems. Nevertheless, due to the...
[ 6 ] - مقایسه‌ی میزان پرداخت از جیب هزینه کل و سهم داروی بیماران سرطان خون، قبل و بعد از اجرای طرح تحول نظام سلامت در ساری
Background and purpose: In many countries, measurements are taken to support cancer patients. In Iran the high costs of cancers and increasing incidence of cancer have made health system authorities to plan for this issue as a top priority of healthcare reform program. The aim of this study was to evaluate the performance of this program in cancer patients in Sari Imam Khomeini teaching hospita...
[ 7 ] - بررسی آلودگی میکروبی کرم های مرطوب کننده موجود در بازار ایران
Background and purpose: There is a high risk of pathogen contamination in poor quality cosmetic products that are illegally smuggled into our country. Such contaminations can be easily passed to consumers and endanger their health. In this study the microbial contamination were investigated in some nonstandard moisturizing creams found in poor quality markets and standard creams from drug store...
[ 8 ] - بررسی تأثیر عوامل فرمولاسیون بر ویژگی های امولژل اسپیرونولاکتون 5 درصد
Background and purpose: Hirsutism, the growing unwanted terminal hair, is one of the disorders which affect life style. Spironolactone is one of the common drugs used in treatment of hirsutism. Topical preparation has been focused in many researches due to side effects after oral administration. In this study, the effect of formulation ingredients on spironolactone emulgel characteristics was e...
[ 9 ] - بررسی پایداری فیزیکی حالت جامد قرص آتنولول و سازگاری آن با برخی از مواد جانبی قرص‌ها
Background and purpose: Oral route is the most frequently used route for drug administration and tablets are the most popular oral drug forms. The study of drug-excepient compatibility is an important process in development of a stable solid dosage form. Incompatibility between drugs and excipients can alter the stability and bioavailability of drugs, thereby affecting its safety and/or efficac...
[ 10 ] - بررسی پایداری فیزیکی حالت جامد و سازگاری پیروکسیکام با مواد جانبی قرص‌ها توسط روش‌های فیزیکوشیمیایی
Background and purpose: The pharmaceutical excipients can be incompatible with drug or other excipients. Thus, for each material, compatibility with formulation components and packaging materials should be examined. The dissolution of a drug has an important role in its bioavailability. Any change in the physico-chemical properties can result in changes in the drug release, and furthermore in i...
[ 11 ] - بررسی تأثیر اعمال حرارت بر کنترل سرعت آزادسازی تئوفیلین از ماتریس‌های حاوی پلیمرهای اودراجیت RS و M4K HPMC با استفاده از روش مایع به جامد
Background and purpose: The potential of liquisolid systems for increasing drug dissolution has been proved in many researches. Recent studies have shown that liquisolid technique is a new and promising method for controlling the dissolution rate of drugs. Based on thermal treating effect on polymer structure, in this study the effects of thermal treating on theophylline release from liquisolid...
[ 12 ] - بررسی تاثیر نوع و میزان پلیمرهای هیدروفیل بر میزان رهش و خصوصیات شناوری قرص های ماتریکسی پروپرانولول هیدروکلراید
Background and purpose: The gastroretentive drug delivery systems can be retained in the stomach due to low bulk density. This assist in improving the oral sustained delivery of drugs that have an absorption window in a particular region of the gastrointestinal tract. These systems release the drug content before reaching the absorption site and provide optimal bioavailability. Several approach...
[ 13 ] - بررسی تاثیر پلیمرهای اودراجیت و HPMC با استفاده از روش مایع به جامد بر کنترل رهش تئوفیلین
Abstract Background and purpose: Recent researches have shown that liquisolid technique is a new and promising method for controlling the dissolution rate of drugs. In this study the effects of Eudragit RS PO and HPMC on theophylline release from liquisolid compacts were evaluated. Materials and methods: Theophylline was dispersed in PEG 200 as the liquid vehicle. Then a binary mixture of car...
[ 14 ] - بررسی تاثیر گلیسرین بر سرعت انحلال ایندومتاسین در سیستم های مایع به جامد (Liquisolid compacts)
Background and purpose: The increasing effect of liquisolid systems on dissolution behavior of poor soluble drugs has been proved. In this research, the effect of glycerin, as a nonvolatile solvent, on release profile of indomethacin was evaluated. Materials and methods: The Avicel as carrier and silica as coating powder material in 20: 1 ratio were used. Indomethacin was dispersed in glyc...