Feraidoon Negahdar

Department of Anatomical Sciences, Iran University of Medical Sciences, Tehran, Iran.

[ 1 ] - Berberine Chloride Pretreatment Exhibits Neuroprotective Effect Against 6-Hydroxydopamine-Induced Neuronal Insult in Rat

Parkinson’s disease (PD) is a rather common movement disorder as a result of the degeneration of dopaminergic neurons within the substantianigra. Current treatments for PD afford symptomatic relief with no prevention of disease progression. Due to the neuroprotective and anti-apoptotic potential of the isoquinoline alkaloid berberine (BBR), this study was conducted to assess whether BBR pretrea...

[ 2 ] - Correlation Between Functional Balance and Mobility Tests and Postural Sway Measures in Dual Task Paradigm in Parkinson’s Disease (a Pilot Study)

Objective: The present study was aimed to correlate the clinical tests with the laboratory measures under dual task conditions in Parkinson's disease (PD). Materials and Methods: Eleven people with idiopathic PD (Modified Hoehn and Yahr scores 1-3) were selected by simple non-probability sampling. Center of pressure (COP) data obtained by force platform was used to calculate mean total velocity...

[ 3 ] - Berberine Chloride Pretreatment Exhibits Neuroprotective Effect Against 6-Hydroxydopamine-Induced Neuronal Insult in Rat

Parkinson’s disease (PD) is a rather common movement disorder as a result of the degeneration of dopaminergic neurons within the substantianigra. Current treatments for PD afford symptomatic relief with no prevention of disease progression. Due to the neuroprotective and anti-apoptotic potential of the isoquinoline alkaloid berberine (BBR), this study was conducted to assess whether BBR pretrea...