Taghi Golmohammadi
Department of Biochemistry, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
[ 1 ] - Effects of resveratrol on crosstalk between canonical β-catenin/Wnt and FOXO pathways in coronary artery disease patients with metabolic syndrome: a case control study
Background: Coronary artery disease (CAD) is the major cause of mortality and morbidity worldwide. The aim of this study was to explore the effect of resveratrol (RES) on Canonical β-catenin/Wnt and forkhead box O (FOXO) pathways in CAD patients.Method: We performed this study on 10 metabolic syndrome patients with three-vessel CAD and 10 sex-aged matched healthy subjects. The effects of RES on...
[ 2 ] - Effects of resveratrol on crosstalk between canonical β-catenin/Wnt and FOXO pathways in coronary artery disease patients with metabolic syndrome: a case control study
Background: Coronary artery disease (CAD) is the major cause of mortality and morbidity worldwide. The aim of this study was to explore the effect of resveratrol (RES) on Canonical β-catenin/Wnt and forkhead box O (FOXO) pathways in CAD patients.Method: We performed this study on 10 metabolic syndrome patients with three-vessel CAD and 10 sex-aged matched healthy subjects. The effects of RES on...
[ 3 ] - Cytotoxicity of Subtoxic AgNP in Human Hepatoma Cell Line (HepG2) after Long-Term Exposure
Background: We aimed at evaluating the toxicity effects of low (subtoxic) concentrations of silver nanoparticles (AgNP, 5-10 nm) in human hepatoblastoma (HepG2) cell line after and during a period of about one month. Methods: XTT and MTT assays were used to draw a dose-response curve IC50 (half maximal inhibitory concentration) value of the AgNP on HepG2 cells was calculated to be 2.75-3.0 mg/l...
[ 4 ] - تعیین فعالیت آنزیم تیمیدین فسفریلاز گلبولهای سفید و تیمیدین پلاسما در بیماران MNGIE بهروش کروماتوگرافی مایع با کارایی بالا- فاز معکوس (RP-HPLC)
Background: Thymidine phosphorylase (TP) catalyses the conversion of thymidine into thymine. Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is an autosomal recessive disease which is caused by mutations in the nuclear gene encoding TP, bringing about severe impairment of TP-enzyme specific activity and accumulation of thymidine in plasma. The clinical manifestations of MNGIE are ...
[ 5 ] - بررسی ارتباط غلظت سرب در خون و آغوز مادر، خون جنین و وزن نوزاد هنگام تولد در مناطق آلوده و غیرآلوده ایران
Background: Lead poisoning has proven to be one of the most important environmental health problems among developing countries with both direct and indirect effects on human life. Lead is known to cross the blood-brain barrier and placenta, and accumulates in soft and hard tissues. Lead can be excreted in urine, stool, milk, sweat, nails and saliva. During pregnancy and lactation, lead is relea...
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