Sedighe Fadaye Vatan

Research and development, Kish Medipharm Company

[ 1 ] - Validated Spectrophtometric Method for Simultaneous Determination of Bupernorphine and Naloxone in Pharmaceutical Dosage Forms

Buprenorphine is a partial mu agonist and kappa antagonist which is used for the treatment of pain and opioid addiction. A mixture of buprenorphine hydrochloride and naloxone hydrochloride has been approved for the treatment of opioid dependence.In this study a third order derivative spectrophotometric method based on zero-crossing technique has been used for the simultaneous determination of b...

[ 2 ] - Validated Spectrophtometric Method for Simultaneous Determination of Bupernorphine and Naloxone in Pharmaceutical Dosage Forms

Buprenorphine is a partial mu agonist and kappa antagonist which is used for the treatment of pain and opioid addiction. A mixture of buprenorphine hydrochloride and naloxone hydrochloride has been approved for the treatment of opioid dependence.In this study a third order derivative spectrophotometric method based on zero-crossing technique has been used for the simultaneous determination of b...