Ali Fattahi

Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.

[ 1 ] - De-Esterified Tragacanth Microspheres Loaded into Eudragit S-100 Coated Capsules for Colon-Targeted Delivery

The objective of this study was to develop a novel bacterially-triggered micro-particular system of de-esterified tragacanth (DET) in combination with Eudragit S-100 coated capsules for colon drug delivery of 5-fluorouracil (5-FU) using microemulsion method. The loading study was conducted at different drug-to-polymer ratios and cross-linker concentrations. The maximum loading efficiency was ac...

[ 2 ] - Biosynthesis, Characterization, Antimicrobial and Cytotoxic Effects of Silver Nanoparticles Using Nigella arvensis Seed Extract

The biogenic synthesis of metal nanomaterial offers an environmentally benign alternative to the traditional chemical synthesis routes. In the present study, the green synthesis of silver nanoparticles (AgNPs) from aqueous solution of silver nitrate (AgNO3) by using Nigella arvensis L. seed powder extract (NSPE) has been reported. AgNPs were characterized by UV–vis absorption spectroscopy with ...

[ 3 ] - De-Esterified Tragacanth Microspheres Loaded into Eudragit S-100 Coated Capsules for Colon-Targeted Delivery

The objective of this study was to develop a novel bacterially-triggered micro-particular system of de-esterified tragacanth (DET) in combination with Eudragit S-100 coated capsules for colon drug delivery of 5-fluorouracil (5-FU) using microemulsion method. The loading study was conducted at different drug-to-polymer ratios and cross-linker concentrations. The maximum loading efficiency was ac...

[ 4 ] - Biosynthesis, Characterization, Antimicrobial and Cytotoxic Effects of Silver Nanoparticles Using Nigella arvensis Seed Extract

The biogenic synthesis of metal nanomaterial offers an environmentally benign alternative to the traditional chemical synthesis routes. In the present study, the green synthesis of silver nanoparticles (AgNPs) from aqueous solution of silver nitrate (AgNO3) by using Nigella arvensis L. seed powder extract (NSPE) has been reported. AgNPs were characterized by UV–vis absorption spectroscopy with ...

[ 5 ] - بهینه‌سازی فرایند انکپسوله سازی دارو در میکروذره های کروی چیتوسان با استفاده از روش الکترواسپری هم‌محور

میکرو و نانو ذره ­ها در دهه ­های اخیر به‌عنوان حامل ­های زیست‌تخریب‌پذیر(داربست) برای تحویل و رهش کنترل‌شده‌ی عامل­ های درمانی گوناگونی مانند داروها، پروتئین‌ها، سلول­ ها و  ژن­ها، گسترش پیدا کردند. در این پژوهش، تولید میکروذره­ های کروی چیتوسان و بارگذاری هم‌زمان رتینوئیک اسید در این میکروذره­ های کروی بر پایه‌ی روش الکترواسپری هم­محور به روش آماری سطح پاسخ مورد بررسی قرا...