Anayatollah Salimi
school of pharmacy, nanotechnology research center, DEPARTMENT OF PHARMACEUTICS
[ 1 ] - Loratadine- Loaded Thermoresponsive Hydogel : Characterization and Ex-vivo Rabbit Cornea Permeability Studies
Poor bioavailability of ophthalmic drops is mainly due to drainage through the nasal-lacrimal duct and a very low permeability through corneal epithelium. The aim of our study was to prepare and characterize an ocular hydrogel of loratadine, as an example of a lipophilic drug, to increase drug concentration and residence time at the site of action in the eye. In this study,a 23full factorial de...
[ 2 ] - Loratadine- Loaded Thermoresponsive Hydogel : Characterization and Ex-vivo Rabbit Cornea Permeability Studies
Poor bioavailability of ophthalmic drops is mainly due to drainage through the nasal-lacrimal duct and a very low permeability through corneal epithelium. The aim of our study was to prepare and characterize an ocular hydrogel of loratadine, as an example of a lipophilic drug, to increase drug concentration and residence time at the site of action in the eye. In this study,a 23full factorial de...
[ 3 ] - Influence of Chemical Permeation Enhancers on the in vitro Skin Permeation of Minoxidil through Excised Rat Skin: A Mechanistic Study
Abstract: Minoxidil, a pyrimidine derivative (2, 4-diamino-6-piperidinopyrimidine-3-oxide) is the only topical medical treatment with proven efficacy for the treatment of Androgenetic alopecia that shown low skin penetration and bioavailability. The main aim of this research was to investigate the effect of some permeation enhancers on the in vitro skin permeability of minoxidil . Minoxid...
[ 4 ] - Developing a Corpus-Based Word List in Pharmacy Research Articles: A Focus on Academic Culture
The present corpus-based lexical study reports the development of a Pharmacy Academic Word List (PAWL); a list of the most frequent words from a corpus of 3,458,445 tokens made up of 800 most recent pharmacy texts including research articles, review articles, and short communications in four sub-disciplines of pharmacy. WordSmith (Scott, 2017) and AntWordProfiler (Anthony, 2014) were used to sc...
[ 5 ] - The Effect of Various Penetration Enhancers on the Octyl Methoxycinnamate Permeability: Mechanisms of Action Study
Octyl methoxycinnamate is one of the ingredients in sunscreen products. The main aim of this study was to investigate the effect of different enhancers of in vitro skin permeability of Octyl methoxycinnamate. Octyl methoxycinnamate permeability parameters were evaluated through the whole skin of the rat with and without chemical enhancers including eucalyptus oil, urea, menthol and olive ...
[ 6 ] - Tadalafil Transdermal Drug Delivery Using Microemulsion Formulation in Laboratory Model
Background and purpose: Tadalafil has gained wide clinical acceptance in treatment of erectile dysfunction due to its long treatment window and lower potential for visual impairment. Transdermal drug delivery prevents systemic elimination, drug-drug and food-drug interactions, and reduces side effects by reducing the dose of the drug. The aim of this study was to evaluate the effect of microemu...