Shahram Ala
Department of Clinical Pharmacy, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran.
[ 1 ] - Cotreatment with Furosemide and Hypertonic Saline Decreases Serum Neutrophil Gelatinase-associated Lipocalin (NGAL) and Serum Creatinine Concentrations in Traumatic Brain Injury: A Randomized, Single-Blind Clinical Trial
Acute kidney injury (AKI) occurs both after traumatic brain injury (TBI) and after hypertonic saline administration; furosemide may be useful in preventing AKI indirectly. Serum neutrophil gelatinase-associated lipocalin (sNGAL) is superior to serum creatinine (sCr) in diagnosing early AKI. We compared the administration of hypertonic saline plus furosemide (HTS+F) versus hypertonic saline (HTS...
[ 2 ] - Effectiveness of Vitamin D Supplement Therapy in Chronic Stable Schizophrenic Male Patients: A Randomized Controlled Trial
In this study, the aim was to determine whether adding vitamin D to the standard therapeutic regimen of schizophrenic male patients with inadequate vitamin D status could improve some aspects of the symptom burden or not. This study was an open parallel label randomized clinical trial. Eighty patients with chronic stable schizophrenia with residual symptoms and Vitamin D deficiency were recruit...
[ 3 ] - Comparison of Dabigatran vs. Warfarin in Acute Vnous Thromboemboly: Systematic Review
abstract:Acute Venous Thromboembolism (VTE) is a common disease associated with the significant morbidity and mortality. We reviewed clinical outcomes systematically with Dabigatran as a direct oral anticoagulants (DOAC) for treatment of acute VTE. We used Ovide, PubMed, Cochrane (CENTRAL), EMBASE, Scopus, Science Direct, LILAC(for article written not English) and also Iranian database; Magiran...
[ 4 ] - Negative Correlation between Serum S100B and Leptin Levels in Schizophrenic Patients During Treatment with Clozapine and Risperidone: Preliminary Evidence
Recently, extensive efforts have been made to understand the rate of energy expenditure and the weight gain associated with atypical antipsychotic treatment, including identification of markers of obesity risk. In recent years, leptin, an adipocyte hormone, has gained significant interest in psychiatric disorders. S100B has been considered as a surrogate marker for astrocyte-specific damage in ...
[ 5 ] - Cotreatment with Furosemide and Hypertonic Saline Decreases Serum Neutrophil Gelatinase-associated Lipocalin (NGAL) and Serum Creatinine Concentrations in Traumatic Brain Injury: A Randomized, Single-Blind Clinical Trial
Acute kidney injury (AKI) occurs both after traumatic brain injury (TBI) and after hypertonic saline administration; furosemide may be useful in preventing AKI indirectly. Serum neutrophil gelatinase-associated lipocalin (sNGAL) is superior to serum creatinine (sCr) in diagnosing early AKI. We compared the administration of hypertonic saline plus furosemide (HTS+F) versus hypertonic saline (HTS...
[ 6 ] - Effectiveness of Vitamin D Supplement Therapy in Chronic Stable Schizophrenic Male Patients: A Randomized Controlled Trial
In this study, the aim was to determine whether adding vitamin D to the standard therapeutic regimen of schizophrenic male patients with inadequate vitamin D status could improve some aspects of the symptom burden or not. This study was an open parallel label randomized clinical trial. Eighty patients with chronic stable schizophrenia with residual symptoms and Vitamin D deficiency were recruit...
[ 7 ] - Comparison of Dabigatran vs. Warfarin in Acute Vnous Thromboemboly: Systematic Review
abstract:Acute Venous Thromboembolism (VTE) is a common disease associated with the significant morbidity and mortality. We reviewed clinical outcomes systematically with Dabigatran as a direct oral anticoagulants (DOAC) for treatment of acute VTE. We used Ovide, PubMed, Cochrane (CENTRAL), EMBASE, Scopus, Science Direct, LILAC(for article written not English) and also Iranian database; Magiran...
[ 8 ] - Negative Correlation between Serum S100B and Leptin Levels in Schizophrenic Patients During Treatment with Clozapine and Risperidone: Preliminary Evidence
Recently, extensive efforts have been made to understand the rate of energy expenditure and the weight gain associated with atypical antipsychotic treatment, including identification of markers of obesity risk. In recent years, leptin, an adipocyte hormone, has gained significant interest in psychiatric disorders. S100B has been considered as a surrogate marker for astrocyte-specific damage in ...
[ 9 ] - ارزیابی شیوع و کنترل استرس هایپرگلایسمی بیماران بستری در بخش ICU
Background and purpose: Stress-induced hyperglycemia (SIH) is common in patients in intensive care units (ICUs). It is associated with adverse consequences such as increased length of stay in ICU, increased risk of infections, and high mortality. This study examined the prevalence of SIH and its therapeutic approach in an intensive care unit. Materials and methods: A retrospective descriptiv...
[ 10 ] - ارزیابی مصرف داروهای جلوگیری از زخم های گوارشی ناشی از استرس در بخش های مراقبت های ویژه
Background and purpose: Gastrointestinal complications frequently occur in patients admitted to intensive care units (ICUs). Of these, ulceration and bleeding due to stress-related mucosal disease (SRMD) can lengthen hospitalization and increase mortality. The purpose of this study was to evaluate the risk factors of SRMD in patients and review the rational use of SUP drugs in ICU. Materials...
[ 11 ] - بررسی دموگرافیک بیماران تحت همودیالیز در شهر ساری در سال 1392
Background and purpose: Chronic kidney disease (CKD) is a permanent debilitating disease that is accompanied by many complications. Patients suffering from CKD need dialysis for survival if kidney transplant is not performed for them. The rate of CKD and patients undergoing dialysis is increasing in Iran but there is a lack of information about the burden of disease. The aims of this study were...
[ 12 ] - بررسی تاثیر پماد کاپسایسین (کاپسیان 0.03 درصد) در درمان خارش بیماران همودیالیزی
Background and purpose: Pruritus is one of the common problems in hemodialysis patients with end stage renal disease. Approximately, 60% of these patients suffer from this condition. There are several causes for pruritus, thus, various treatments are applied in order to control it. The aim of this study was to evaluate the therapeutic effect of capsaicin on pruritus, compared with placebo, in...
[ 13 ] - بررسی غلظت پلاسمایی روی و مس و نسبت آنها در بیماران مبتلا به آرتریت روماتوئید و مقایسه آنها با گروه شاهد
Background and Purpose: The role of trace elements (Cu, Zn) in chronic inflammatory states has provided interest, as many of them are co-factors in metabolic processes, involving arthricular tissues and immune system function. The purpose of the current study was to evaluate zinc and copper plasma concentration in rheumatoid arthritis (RA) patients, who were referred to the Sari Outpatient Cl...
[ 14 ] - آنالیز محلول گاواژ بیمارستانی و میزان تامین کالری و پروتئین مورد نیاز بیماران در بخش مراقبت های ویژه بیمارستان امام خمینی (ره) ساری 85-84
Background and Purpose: Malnutrition is a major problem within intensive care units (ICU) affecting the outcome of patients. In Imam Khomeini Hospital, patients were fed with gavage solutions prepared in the kitchen of hospitals, however, its' nutritional value has not been studied at present time. The aim of this study was to analyze the gavage solution and to compare the calculated nutritio...
[ 15 ] - بررسی اثرات ان - استیل سیستئین در جلوگیری از نفروپاتی مواد حاجب ناشی از آنژیوگرافی عروق کرونر در افراد با عملکرد کلیوی طبیعی
Background and purpose: N-Acetylcysteine (NAC) has been found to reduce the risk of Contrast Induced Nephropathy (CIN) in chronic renal insufficiency after CT imaging with contrast enhancement. The purpose of the current study was to evaluate the efficacy of NAC, for the prevention of CIN in normal renal functioning patients undergoing coronary angiography. Materials and Methods: We prospe...
[ 16 ] - تاثیر پماد مترونیدازول در کاهش درد بیماران بعد از هموروئیدکتومی
Background and purpose: Topical metronidazole (10 percent) has been previously demonstrated to decrease post operative pain after hemorrhoidectomy. The aim of this study was to evaluate the effect of topical metronidazole (10 percent) on postoperative and after defecation pains of hemorrhoidectomy. Materials and Methods: A double-blind randomized trial was conducted to compare post- hemorr...
[ 17 ] - Dose levotyroxine consumption in hypothyroid patients before dinner change the levels of TSH and T4?
Background: Levothyroxine is commonly used in the treatment of patients with hypothyroidism. Levothyroxine is often administered in the morning, on an empty stomach, to increase its absorption. However, many patients have trouble for taking levothyroxine in the morning. The aim of this study was to evaluate the effect of changing administration time of levothyroxine from before breakfast ...
[ 18 ] - بررسی خطاهای دارویی در بخش های داخلی بیمارستان امام سجاد(ع) رامسر در بهار و تابستان 1396
مقدمه اشتباهات دارویی رخداد شایع بالقوه خطرناک است که میتواند در سیستم درمان به عنوان یکی از چالشها و معیارهای سنجش ایمنی بیمار مورد استفاده قرار گیرد.در این مطالعه، برخی از خطاهای رایج دارویی در بخشهای داخلی بیمارستان امام سجاد (ع) رامسر، مورد بررسی قرار گرفت. روش کار نوع مطالعه توصیفی- مقطعی و جامعه مورد مطالعه شامل200پرونده بیمار بستری ...
[ 20 ] - بررسی مصرف منطقی داروهای مسکن تزریقی در بخش های اورژانس و جراحی بیمارستان امام سجاد (ع) رامسر
مقدمه: هدف از انجام پژوهش حاضر بررسی الگوی مصرف منطقی داروهای مسکن تزریقی اعم از اپیوئید و غیر اپیوئید در بیماران بستری در بخش های جراحی و اورژانس بیمارستان امام سجاد رامسر بوده است. روش کار: این مطالعه به شکل توصیفی و گذشته نگر، در بهار و تابستان 1395، بر روی 1181 پرونده بیماران دریافت کننده داروی مسکن تزریقی بستری شد...
[ 21 ] - Role of Pharmacist in Reducing the Rate of Drug Interactions; An Experience from North of Iran
Background and purpose: Drug interactions are one of the serious subsets of medication errors and occur when the effects or toxicity of one drug are affected by another. This study aimed to investigate drug interactions and the role of pharmacist in reducing drug interactions in Ramsar Imam Sajjad Hospital, Iran. Materials and methods: This cross-sectional study was performed in all prescripti...
[ 22 ] - Efficacy of Sucralfate Ointment in Prevention of Acute Proctitis in Cancer Patients: a Randomized Controlled Clinical Trial
Background: Acute radiation proctitis (ARP) is a usual adverse effect in patients undergoing pelvic radiotherapy. The symptoms include diarrhea, rectal blood or mucus discharge, fecal urgency and tenesmus with pain. Sucralfate, an aluminum-based salt of sucrose octasulfate, is a cytoprotective agent that forms a coating barrier at injured sites by adhering to mucoproteins. It has been used in t...
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