Faramarz Masjedian Jazi
Dept. of Microbiology, Iran University of Medical Sciences, Tehran. Iran
[ 1 ] - Species-specific PCR for the Diagnosis and Determination of Antibiotic Susceptibilities of Brucella Strains Isolated from Tehran, Iran
Background: Brucellosis is an endemic zoonotic disease in the Middle East. This study intended to design a uniplex PCR assay for the detection and differentiation of Brucella at the species level and determining the antibiotic susceptibility pattern of Brucella in Iran. Methods: Sixty-eight Brucella specimens (38 an...
[ 2 ] - نگاهی مجدد به مشکلات تشخیصی بروسلوز در ایران
براساس گزارشهای متعدد، تشخیص بروسلوزیس در ایران با تأخیر همراه است. درصد بسیاری از بیماران بستری در بیمارستانها پیش از درمان با آنتیبیوتیکهای اختصاصی عمدتا بر اثر تشخیصهای نادرست با داروهای متفرقه و اغلب تک‌دارویی بر اثر تشخیص ناصحیح درمان شدهاند. چون در بروسلوزیس، درمانهای مبتنی بر شواهد آزمایشگاهی و بهکارگیری روش‌های تشخیصی با حساسیت قابل‌قبول اهمیت ویژه‌ای در تشخیص نهایی دارد. مطال...
[ 3 ] - Prevalence of proline racemase/ hydroxyproline epimerase gene in human brucella isolates in Iran
Background: Human brucellosis is a zoonotic disease caused by Brucella melitensis, Brucella abortus, and Brucella suis. Brucella causes a chronic disease, which subverts the immune defense system of their hosts. In this study, the prevalence of an important Brucella virulence determinant, PrpA, which can modulate immune response, was determined in human isolates. Methods: Polymerase chain reac...
[ 4 ] - Prevalence of flmA, flmH, mrkA, ecpA, and mrkD virulence genes affecting biofilm formation in clinical isolates of K. pneumonia
Background: Klebsiella pneumoniae is an opportunistic microorganism causing nosocomial infection all over the world .This study aimed to investigate the prevalence of biofilm formation in K. pneumoniae isolated from patients and its correlation with the virulence factors. Materials and Methods: Biochemical tests were used for the identification of K. pneumonia isolated from patients referred to...
[ 5 ] - Investigating the prevalence of resistance genes in Listeria monocytogenes isolated from food and clinical samples
Background: Listeriosis can be fatal for vulnerable groups of society. The disease has been widespread in recent years due to the large consumption of dairy and meat products. There is little information about the susceptibility of antibiotics and the pattern of Listeria monostigenesis gene resistance in Iranian society. Accordingly, the present study was conducted to investigate the antibiotic...
[ 6 ] - Antibiotic Susceptibility Pattern and Distribution of Virulence Factors Among Klebsiella pneumoniae Isolated from Healthy Volunteers
Background and Objective: The healthy people’s fecal flora in the community represents a large potential reservoir. Therefore, the current study aimed to detect antibiotic resistance patterns and virulence factors in Klebsiella pneumoniae isolated from healthy volunteers’ feces. Materials and Methods: Three hundred and fifty stool specimens were collected from sales rep healthy individuals ref...
[ 7 ] - Evaluation of the presence and time-variable expression levels of rpoS, relA and mazf genes during biofilm formation in Staphylococcus epidermidis
Background and purpose:Staphylococcus epidermidis is an opportunistic pathogen that is involved in the development of infections associated with the use of implants and medical devices. Biofilm formation is one of the most important virulence factors of this microorganism, which vastly depends on various factors, including different proteins. In the present study, the expression levels of three...
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