Peyman Eshghi

[ 1 ] - Evaluation of Aryoseven Safety (Recombinant Activated Factor VII) in Patients with Bleeding Disorders (An Observational Post-Marketing Surveillance Study)

Background: Recombinant activated factor VII induces hemostasis in patients with coagulopathy disorders. AryoSeven™ as a safe Iranian Recombinant activated factor VII has been available on our market. This study was performed to establish the safety of AryoSeven on patients with coagulopathy disorder. Methods: This single-center, descriptive,...

[ 2 ] - Selection Bias in reporting the prevalence of Transfusion Transmitted Infection Diseases in Iranian Hemophiliacs

[ 3 ] - مقایسه عواقب حقوقی، اجتماعی و اقتصادی ناشی از بیماری‌های منتقل شونده از راه خون در ایران و جهان

  چکید ه   سابقه و هدف   توجه جهانی به مشکل بیماری‌های عفونی منتقله از طریق خون و فرآورده‌های مشتق از پلاسما (TTI) ، با گزارش اولین بیمار هموفیل مبتلا به ایدز و هپاتیت C ، موجب عواقب حقوقی، اجتماعی و اقتصادی در کشورهای توسعه یافته و در حال توسعه گردید. در این مقاله به مقایسه این عواقب در ایران و سایر کشورها پرداخته شده است.   مواد و روش‌ها   مرور سیستماتیک بر 29 مقاله به دست آمده از بانک‌های اط...

[ 4 ] - Frequency of Decreased Bone Mineral Density and Its Risk Factors during Childhood among Iranian Hemophilia Patients

This study was undertaken to assess the frequency of decreased bone mineral density and its risk factors as well as its impact on the quality of life during childhood among hemophiliac patients. Materials and Methods: Thirty seven children with severe hemophilia A and B, referred to Mofid Children’s Hospital during 2010, were selected. For all patients the joint score, body mass indexes, bone...

[ 5 ] - Novel Colchicine Analogues Target Mitochondrial PT Pores Using Free Tubulins and Induce ROS-Mediated Apoptosis in Cancerous Lymphocytes

B-acute lymphoblastic leukemia (B-ALL) is the frequent pediatric malignity. Chemotherapy is the most practical approaches to deal with such malignancies. Microtubule-targeted agents are one of the most strategic drugs which formerly use in chemotherapy.Although,colchicine-binding anti-tubulin agents exhibited promising effects in clinical trials, their exact mechanism of action is not fully und...

[ 6 ] - Novel Colchicine Analogues Target Mitochondrial PT Pores Using Free Tubulins and Induce ROS-Mediated Apoptosis in Cancerous Lymphocytes

B-acute lymphoblastic leukemia (B-ALL) is the frequent pediatric malignity. Chemotherapy is the most practical approaches to deal with such malignancies. Microtubule-targeted agents are one of the most strategic drugs which formerly use in chemotherapy.Although,colchicine-binding anti-tubulin agents exhibited promising effects in clinical trials, their exact mechanism of action is not fully und...

[ 7 ] - Complications of Combined Treatment with Deferiprone and Desferrioxamine in Thalassemic Patients

Although successful iron chelation with deferiprone is associated with significant complications, patient’s compliance with medication regimens is of a high priority. The present study did evaluate the complications and compliance of domestically-manufactured deferiprone combined with desferrioxamine for iron chelation therapy. A total of 32 major beta thalassemic patients with cardiomyopathy w...