Nasser Rakhshani
Gastrointestinal and Liver Diseases Research Center, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran
[ 1 ] - Hirschsprung Disease Diagnosis: Calretinin Marker Role in Determining the Presence or Absence of Ganglion Cells
Background: Hirschsprung disease is a complex genetic disorder of the enteric nervous system (ENS), often called congenital aganglionic megacolon and characterized by the absence of enteric neurons along a variable length of the intestine. The definitive diagnosis of Hirschsprung disease relies on histologic and/or histochemical staining of sections fr...
[ 2 ] - Jaw Pain as a First Presentation in the Diagnosis of Breast Cancer
The oral cavity is uncommon site for metastatic disease usually discovered secondary to malignancy. We encountered with a rare case in which metastasis to mandibular bone was the first clinical sign in the diagnosis of breast cancer without any radiographic findings. A 49-yr-old premenopausal woman, was referred to the Department of Medical Oncology of Imam Hossein Hospital, Shahid Beheshti Uni...
[ 3 ] - Polymorphism of IL-28B Gene (rs12979860) in HCV Genotype 1 Patients Treated by Pegylated Interferon and Ribavirin
Background: Nowadays, the immune response to hepatitis C (HCV) treatment has become a crucial issue mostly due to the interleukin 28B (IL-28B) polymorphism effects in chronic HCV patients. The aim of this study was to detect the polymorphism of IL-28B gene (rs12979860) in HCV genotype 1 patients treated with pegylated Interferon and Ribavirin. Methods...
[ 4 ] - The Relationship between Size of Adenocarcinoma of Colon and Lymph Node Involvement
Background and Objectives: Involvement of lymph nodes is an important prognostic factor in the most cancers, including colorectal cancer. In the recent years, invasion to blood and lymphatic vessels has been shown to predict involvement of lymph nodes and the number of involved nodes has been less studied issue. The aim of this study was determination of the relationship between the size of col...
[ 5 ] - Ureteral Endometriosis: A Report Of Two Cases
Endometriosis is the presence of benign endometrial glands and stroma outside the uterus. Urinary system involvement by endometriosis is a rare occurrence accounting for only 1.5 % of all endometriosis cases. Case 1. The patient was a 41 years old woman admitted for right flank pain. The physical and gynaecologic examination was unyielding. Intravenous urography (IVU) revealed sten...
[ 6 ] - ارتباط بیان مهارکننده عامل القایی هیپوکسی-1 آلفا (HIF1AN) با میزان تهاجم عروقی در سرطان روده بزرگ
زمینه: کمبود فشار اکسیژن (هیپوکسی) یک پدیده شایع در تومورهای انسانی است که با افزایش القای فرآیند رگزایی (آنژیوژنزیس) موجب رشد٬ بقا و تهاجم تومور میشود. مهارکننده عامل القایی هیپوکسی ((HIF1AN از طریق اتصال به یک سری زیر واحدهای پروتئین HIF1α به نام کپ بایندیگ پروتئین پی 300 (CBP/P300) موجب مهار عامل القایی هیپوکسی (HIF1α) میشود. هدف: مطالعه به منظور تعیین ارتباط بیان مهارکننده عامل القایی هی...
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