Maliheh Khoddami
Pediatric Pathology Research Center, Research Institute for Children Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran
[ 1 ] - Herpes Simplex Virus and Langerhans Cell Histiocytosis
Background and objective: Langerhans cell histiocytosis (LCH) is a rare histiocytic proliferative disorder of unknown etiology and mainly affects young children. The histological feature is granuloma-like proliferation of langerhans-type dendritic cells. Although the possible role of viruses such as Epstein-Barr virus (EBV, Human Herpes virus -4</...
[ 2 ] - Correlation between Gleason scores in needle biopsy and corresponding radical prostatectomy specimens. A twelve-year review.
Background: Presence of discordance between the Gleason score on needle biopsy and the score of radical prostatectomy specimen is common and universal. In this study, we determined the accuracy of Gleason grading of biopsies in predicting histological grading of radical prostatectomy specimens and the degree of overgrading and undergrading of prostatic adenocarcinoma i...
[ 3 ] - Diagnostic Accuracy of Frozen Section in Ovarian Tumors: A 12-Year Review
Background and objective: To determine the diagnostic accuracy and pitfalls of frozen section in ovarian tumors in one of the largest university affiliated gynecologic oncology centers in Tehran, and determine the cause of discrepancies. Materials and Methods: We retrospectively analyzed the results of frozen section and permanent diagnoses of ovarian masses by reviewing the reports in the dep...
[ 4 ] - Borderline Ovarian Serous Adenofibromatous tumor with Prominent Micropapillary Pattern
Ovarian borderline serous tumors are uncommon. Combination of borderline serous adenofibromatous tumor and prominent micro papillary architecture is not previously reported. We report a case of borderline papillary serous adenofibromatous tumor (also called serous adenocarcinofibroma) with extensive micropapillary pattern in a 27 year-old married woman. She was infertile and presented with diff...
[ 5 ] - ارتباط ویروسهای DNA دار و لانگرهانس سل هیستیوسیتوزیس در کودکان ایرانی
سابقه و هدف: لانگرهانس هیستیوسیتوزیس یک بیماری نادر می باشد که بافت های مختلفی را در گیر میکند. از آنجائیکه ویروسها بعنوان عوامل احتمالی ایجاد لانگرهانس سل هیستیوسیتوزیس مطرح شده اند. لذا این مطالعه به منظور بررسی ارتباط ویروسهای DNA دار و لانگرهانس سل هیستیوسیتوزیس در کودکان ایرانی انجام شد. مواد و روش ها: در این مطالعه مورد-شاهدی، بلوک های پارافینی 48 بیمار با تشخیص بالینی و میکروسکپی لانگرها...
[ 6 ] - Absence of Human Papillomavirus in Benign and Malignant Breast Tissue
Background & Objective: Malignant breast tumors, which are one of the most important deadly cancers in women, like many other cancers, are proposed to be related to viruses etiologically. Proper management of breast carcinoma necessitates an identification of the etiological factors. Human Papillomavirus is considered to have an etiological role in breast carcinoma. We...