Mehdi Shekarabi
Department of Allergy and Clinical Immunology, Iran University of Medical Sciences, Tehran, Iran.
[ 1 ] - Otitis Media with Effusion in Children and the Impact of Risk Factors on Serum Cytokine Levels
Introduction:To evaluate the role of allergic-type and infectious-type cytokines in children with chronic otitis media with effusion (OME) Materials and Methods:We investigated serum levels of interleukins (IL)-4, IL-5, and IL-13, along with interferon-gamma (IFN-γ) and tumor necrosis factor-alpha (TNF-α), by enzyme-linked immunosorbent assay (ELISA) in 35 children with OME and 28 healthy contr...
[ 2 ] - بررسی فراوانی عفونت سل نهفته در بیماران مبتلا به سرطان ریه و مقایسه آن با افراد سالم
Background: Lung cancer is the fifth most common cancer in Iran, with 10.5 and 1.5 per 100,000 in males and females, respectively. The study of latent tuberculosis infection (LTBi) in patients with lung cancer is significant due to the possibility of its activation during chemotherapy and increased mortality. Therefore, the aim of this study was to compare the prevalence of LTBi in patients wit...
[ 3 ] - مقایسه بیماران مبتلا به دیابت پنهان خودایمن و دیابت نوع 1 از نظر سابقه خانوادگی دیابت
Background: Latent autoimmune diabetes of adults (LADA) is a form of autoimmune diabetes initially managed with oral hypoglycemic agents before becoming insulin requiring. One of the LADA risk factors is family history of diabetes (FHD) that less well understood. Our aim was investigate the influence of FHD on the incidence of LADA compared with those for type 1. Methods: In this cross section...
[ 4 ] - Study of NGEP expression in androgen sensitive prostate cancer cells: A potential target for immunotherapy
Background: Prostate cancer is one of the leading causes of cancer deaths among men. New gene expressed in prostate (NGEP), is a prostate-specific gene expressed only in normal prostate and prostate cancer tissue. Because of its selective expression in prostate cancer cell surface, NGEP is a potential immunotherapeutic target. To target the NGEP in prostate cancer, it is essential to investig...
[ 5 ] - Comparison of Epstein Barr virus antibodies and Tcell cytokines production in patients with multiple sclerosis and healthy individuals
Abstract Background: Multiple sclerosis (MS) is the most common autoimmune disease of central nervous system with destruction of myelin sheath mediated by auto reactive CD4+ T Lymphocytes. Because of the possible role of Epstein-Barr virus in etiology of MS and T cells immune response, the aim of this study was to evaluate anti-Epstein Barr virus antibodies as a marker of reactivity and p...
[ 6 ] - فراوانی دیابت پنهان خودایمن در بیماران با فنوتیپ دیابت نوع 2 در قم
Background: Latent autoimmune diabetes of adults (LADA) is a slowly progressive form of diabetes managed with diet and oral hypoglycemic agents before becoming insulin requiring. Islet autoantibodies are used for differential diagnosis between LADA and Type 2 diabetes mellitus. The aims of this study were to investigate the frequency of LADA using islet autontibodies in population with T2DM and...
[ 7 ] - The Effect of SB431542, TGF-β Receptor Inhibitor, on HCV Replication in PBMCs of Patients with Chronic Hepatitis
Background and Aims: TGF-β is an effective cytokine in the viral replication cycle, which is also highly relevant to the pathogenesis of some viral infections. TGF-β induction by viral proteins is one of the ways to escape the virus from the immune system by inhibiting interferon signaling and other immune system factors. In recent years, the role of TGF-β and its inhibitor...
[ 8 ] - بررسی تأثیر تجویز خوراکی پروبیوتیک لاکتوباسیلوس اسیدوفیلوس بر ارتشاح زیرگروه‌های لنفوسیت‌های T در اعضاء لنفاوی جوجه به عنوان مدل آزمایشگاهی
سابقه و هدف: امروزه اثرات سودمند پروبیوتیک ها بر میزبان به خوبی مشخص شده است با این وجود، مکانیسم عملکرد آن به خوبی شناخته نشده و از این رو تحقیقات بسیاری پیرامون آن از جمله در زمینه سیستم ایمنی در حال انجام است. این مطالعه به منظور بررسی اثر باکتری‌های لاکتیک اسید بر رده‌های سلولی T در بافت‌های ایلئوم، لوزه سکوم و بورس فابریسیوس در جوجه، انجام شده است. مواد و روش‌ها : تعداد سی قطعه جوجه در...
Co-Authors