Sedigheh Moradkhani

Nuclear Science Research School, Nuclear Science and Technology Research Institute, Tehran, Iran

[ 1 ] - Radiosynthesis and evaluation of ytterbium-175 labeled bleomycin as therepeutic agent

Introduction: Bleomycins are DNA-binding biomolecules, which can be used as targeted therapy carriers when labeled with particle-emitters such as Yb-175. In this work the development of Yb-175 bleomycin (175Yb-BLM) has been reported. Methods: Yb-175 chloride was obtained by thermal neutron irradiation (3 × 1013 n.cm-2.s-1) of natural Yb2O<...