Alireza Zamani

Department of Immunology-Hematology, School of Medicine | Dental Research Center, Hamadan University of Medical Sciences, Hamadan, Iran

[ 1 ] - Effect of Ibuprofen on IL-1β, TNF-α and PGE2 Levels in Periapical Exudates: A Double Blinded Clinical Trial

Background: Bone resorption is one of the main features of inflammatory periapical lesions and is mainly mediated by interleukin-1 beta (IL-1β), tumor necrosis factoralpha (TNF-α) and prostaglandin-E2 (PGE2). Recent investigations of these lesions revealed that pharmacological modulation may be possible. Objective: The aim of this study was to evaluate the effect of Ibuprofen on IL-1β, TNF-α an...

[ 2 ] - ارزیابی خطاهای روش تحقیق طرحهای تحقیقاتی مصوب در معاونت تحقیقات دانشگاه علوم پزشکی همدان

Introduction: This cross sectional study was conducted to assess methodological errors in proposals of 95 approved research projects introduced to different unites of Hamadan University of Medical Sciences in 2007. Methods: We used a questionnaire able to determine the kind of studies, correct designing of aims, hypothesis, methods and considering ethical codes. SPSS version 16 was used to d...

[ 3 ] - In Vitro Cytotoxic Effects of Cuscuta chinensis Whole Extract on Human Acute Lymphoblastic Leukemia Cell Line

Background: One of the major paths for drug development is the study of bioactivities of natural products. Therefore, the aim of this study was to compare the cytotoxic effects of aqueous extract of whole Cuscuta chinensis Lam., which is a traditional medicinal herb commonly used in Iran and other oriental countries, on the human caucasian acute lymphoblastic leukemia (CCRF-CEM) and another hum...