Mohammad Reza Rezvani
Department of Hematology, Faculty of Allied Medicine, Tehran University of Medical Sciences | Department of Hematology, Faculty of Allied Medicine, Iran University of Medical Sciences | | Immune and Gene Therapy Laboratory, Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden
[ 1 ] - A Novel mAb against a Human CD34 Peptide Reacts with the Native Protein on CD34+ Cells
Background: Human CD34 is a transmembrane glycoprotein which is expressed in human hematopoietic stem cells (HSCs) and the small- vessel endothelial cells of a variety of tissues. CD34 plays a critical role as a marker for diagnosis and classification of leukemia. Anti CD34 antibodies are used for isolation and purification of HSCs from bone marrow, peripheral blood and cord blood. Objective: ...
[ 2 ] - بررسی ارتباط کم خونی فقرآهن وهیپوتیروئیدی اولیه
Abstract Background: Iron deficiency is the most common nutritional deficiencies in the world. So that 15% of the total world population is involved. The present study examined the association between iron deficiency anemia and primary hypothyroidism and the prevalence of iron deficiency anemia and primary hypothyroidism, respectively, in patients with iron deficiency anemia and primar...
[ 3 ] - Polymorphisms within methotrexate pathway genes: Relationship between plasma methotrexate levels, toxicity experienced and outcome in pediatric acute lymphoblastic leukemia
Objective(s): The current study aimed to investigate the relationship of genetic polymorphism and plasma methotrexate (MTX) levels, toxicity experience and event free survival (EFS) in pediatric acute lymphoblastic leukemia (ALL). Materials and Methods: The study included 74 ALL patients. Polymerase chain reaction and genotyping of methy...
[ 4 ] - DNA Methylation and the Expression of the Tumor-Suppressor Genes Protocadherin-10 and Reprimo in Pediatric Acute Lymphoblastic Leukemia
Background: Acute lymphoblastic leukemia (ALL) is the most prevalent hematologic malignancy among children. DNA methylation is well known to play a role in the initiation and progression of cancer. This research aimed to characterize the epigenetic inactivation and gene expression of Protocadherin-10 (PCDH10) and Reprimo (RPRM) in pediatric acute lymphoblastic leukemia, which is associated with...
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