Sussan Kaboudanian Ardestani
Immunology Lab, Institute of Biochemistry and Biophysics, University of Tehran
[ 1 ] - Improved Immunogenicity of Tetanus Toxoid by Brucella abortus S19 LPS Adjuvant
Background: Adjuvants are used to increase the immunogenicity of new generation vaccines, especially those based on recombinant proteins. Despite immunostimulatory properties, the use of bacterial lipopolysaccharide (LPS) as an adjuvant has been hampered due to its toxicity and pyrogenicity. Brucella abortus LPS is less toxic and has no pyrogenic properties compared to LPS from other gram nega...
[ 2 ] - بررسی فعالیت آنزیم آمینوپپتیداز(CD13) N در افرادی با تیتر بالای آنتیبادی ضدبروسلا
Background and Objective: Aminopeptidases remove the amino acids from the N-terminal of proteins and peptides. Aminopeptidase N (CD13) and leucine aminopeptidase are involved in processing and presentation of pathogens to immune cells. Also, enzyme activity in some viral infection and tumors are high. In this study, the activity of CD13 in serum with high level of brucella antibody wa...
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