Seyed Hesamedin Nabavizadeh

[ 1 ] - IL-23 Gene and Protein Expression in Childhood Asthma

Background: Asthma is the chronic inflammation of airways characterized by eosinophilic infiltration, mucus overproduction, airway hyper-responsiveness and airway remodeling. These changes are induced mostly by cytokines which are produced by T helper (Th) 2 cells. Recently, the role of interleukin-23 (IL-23) in the pathogenesis of adultallergic asthma has been studied. Objective: To explore IL...

[ 2 ] - Clinical and Immunological Efficacy of Aspirin Desensitization in Nasal Polyp Patients with Aspirin-Exacerbated Respiratory Disease

This study aimed to investigate the efficacy and the underlining mechanism of aspirindesensitization among patients with Aspirin Exacerbated Respiratory Disease (AERD). Thirtyeightpatients, who had undergone an aspirin challenge test and were diagnosed as havingAERD, were engaged in a double-blind randomized clinical trial. They were divided into twogroups—an active group of patients who went t...

[ 3 ] - Clinical and Immunological Efficacy of Aspirin Desensitization in Nasal Polyp Patients with Aspirin-Exacerbated Respiratory Disease

This study aimed to investigate the efficacy and the underlining mechanism of aspirindesensitization among patients with Aspirin Exacerbated Respiratory Disease (AERD). Thirtyeightpatients, who had undergone an aspirin challenge test and were diagnosed as havingAERD, were engaged in a double-blind randomized clinical trial. They were divided into twogroups—an active group of patients who went t...

[ 4 ] - گزارش یک مورد از تظاهر لوپوس به‌دنبال زنبور گزیدگی

زمینه و هدف: بیماری لوپوس یک بیماری خود ایمنی است که به ‏دنبال آن امکان درگیری ارگان‏های مختلف وجود خواهد داشت. علت بروز آن تاکنون به‏ طور کامل شناخته نشده است، هر چند تأثیر عواملی مانند عوامل محیطی، ژنتیکی و هورمونی در بروز آن مشخص شده است. هدف از این مطالعه، گزارش یک مورد از تظاهر لوپوس به دنبال زنبور گزیدگی بود. روش کار: این مطالعه یک گزارش موردی است که اطلاعات مربوط به بیمار از پرونده و ...

[ 5 ] - Epidemiology of Severe Cutaneous Adverse Drug Reaction and Its HLA Association among Pediatrics

Severe cutaneous adverse drug reaction (SCAR) is considered to be a multifactorial drug side effect. This study was designed to investigate the epidemiology and human leukocyte antigen (HLA)-A and -B gene polymorphisms in pediatric patients with SCAR admitted in tertiary referral center, southwestern of Iran from 2013 to 2017. Demographic data, past allergy and autoimmune history, clinical pres...

[ 6 ] - Epidemiology of Severe Cutaneous Adverse Drug Reaction and Its HLA Association among Pediatrics

Severe cutaneous adverse drug reaction (SCAR) is considered to be a multifactorial drug side effect. This study was designed to investigate the epidemiology and human leukocyte antigen (HLA)-A and -B gene polymorphisms in pediatric patients with SCAR admitted in tertiary referral center, southwestern of Iran from 2013 to 2017. Demographic data, past allergy and autoimmune history, clinical pres...

[ 7 ] - ارزیابی تأثیر اتاق آینه در کاهش هیپربیلی‌روبینمی نوزادی

چکیده: مقدمه و هدف: یرقان یکی از شایع‌ترین مشکلات دوره نوزادی است، اگر چه اکثر یرقان‌های نوزادی خود به خود بهبود می‌یابند، ولی خطر آسیب مغزی ناشی از کرنیکتروس یکی از نگرانی‌های دایمی در این مورد می‌باشد. فتوتراپی یکی از روش‌های رایج و مؤثر در درمان زردی نوزادی می‌باشد که بهبود روش‌های فتوتراپی می‌تواند در پیشگیری از تعویض خون نوزادان مؤثر باشد. در این راستا هدف از این مطالعه ارزیابی تأثیر ...

[ 8 ] - بررسی شاخص های رشد بیماران تالاسمی ماژور

چکیده: مقدمه و هدف: تالاسمی ماژور شدیدترین کم‌خونی همولیتیک شناخته شده و شایع ترین سندرم اختلال تک ژنی می‌باشد که به دلیل شیوع فراوان آن در ایران لازم است از بسیاری جهات مورد بررسی قرار گیرد. با توجه به این که یکی از مهمترین عوارض در این بیماران در صورت عدم درمان مناسب، مشکلات رشد می‌باشد، لذا هدف از این مطالعه بررسی شاخص‌های رشد فیزیکی آنان و مقایسه با افراد سالم است تا وضعیت درمانهای موجو...

[ 9 ] - IL-25 and IL-33 Serum Levels are not Associated with the Type of Allergen Causing Allergic Rhinitis

Background: Fungal aeroallergens might sensitize the airway which in turn produces a specific cytokine profile. Objective: To evaluate the IL-25 and IL-33 profile in patients with fungal allergic rhinitis. Methods: The present study examined patients who were evaluated due to allergic rhinitis (AR) at Emam Reza Hospital of Shiraz, Iran. The all...