Davoud Farajzadeh
Department of Cellular and Molecular Biology, Faculty of Biological Sciences, Azarbaijan Shahid Madani University, Tabriz, Iran.
[ 1 ] - Molecular phylogeny of the family Araceae as inferred from the nuclear ribosomal ITS data
The internal transcribed spacer regions of nuclear ribosomal DNA are widely used to infer phylogenetic relationships in plants. In this study, it was obtained the ITS sequences from 24 samples of Araceae in Iran, representing 3 genera: Arum L., Biarum Schott. and Eminium (Blume) Schott. Phylogenetic analyses were conducted by Bayesian inference and maximum Parsimony methods. Cladistic analysis ...
[ 2 ] - Molecular Epidemiology of Breast Cancer among Iranian-Azeri Population based on P53 Research
Background: This study was done in order to enhance our understanding about molecular and epidemiological features of breast cancer among the Azeri population with special emphasis on the detection of TP53 mutations. We also analyzed the role of the P53codon72 polymorphism (rs1042522) and its role in susceptibility to breast cancer. Methods: ...
[ 3 ] - Review of NKG2D function and its related ligands: review article
The natural killer group 2D (NKG2D) is a transmembrane protein and a member of the CD94/NKG2 family of C-type lectin-like receptors. NKG2D is encoded by the KLRK1 gene, which is located in the NK-gene complex (NKC) placed on chromosomes 6 and 12 in mice and humans, respectively. NKG2D forms a homodimer structure and binds through ectodomains with its related ligands. Each of its monomers consis...
[ 4 ] - فاکتور نکروزدهنده تومور آلفا و راهکارهای مهار آن: مقاله مروری
Tumor necrosis factor-alpha (TNF-α) is a pro-inflammatory cytokine produced by a variety of cells, including hematopoietic and non-hematopoietic cells, malignant cells, macrophages, B lymphocytes, T lymphocytes, natural killer cells, neutrophils, astrocytes, endothelial cells, and smooth muscle cells. TNF-α is a homo-trimeric molecular whose individual subunits are composed of antiparallel beta...