Mohammad Jafar Abdekhodaie

Department of Chemical Engineering, Sharif University of Technology, P.O. Box 11365-8639 Tehran, I.R. Iran

[ 1 ] - Influence of Formulation Parameters on the Release of Diclofenace Sodium from Matrices with Manufacturing Formulation Ingredients

Effects of formulation parameters on the fractional release profile of diclofenac sodium from matrices having the manufacturing formulation ingredients are studied. As a content of cetyl alcohol (rate controlling agent) in the matrix increases, the fractional release decreases. The fractional release increases either by increasing sucrose content outside the granule or by decreasing sucrose...

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